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571 results

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Page 1
The selection and design of GPCR ligands: from concept to the clinic.
Ashton M, Charlton MH, Schwarz MK, Thomas RJ, Whittaker M. Ashton M, et al. Among authors: whittaker m. Comb Chem High Throughput Screen. 2004 Aug;7(5):441-52. doi: 10.2174/1386207043328607. Comb Chem High Throughput Screen. 2004. PMID: 15320711 Review.
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
Armer RE, Ashton MR, Boyd EA, Brennan CJ, Brookfield FA, Gazi L, Gyles SL, Hay PA, Hunter MG, Middlemiss D, Whittaker M, Xue L, Pettipher R. Armer RE, et al. Among authors: whittaker m. J Med Chem. 2005 Oct 6;48(20):6174-7. doi: 10.1021/jm050519b. J Med Chem. 2005. PMID: 16190744
Development of self-indicating resin.
Ichihara O, Sampson D, Whittaker M, Bradley M, Cho JK. Ichihara O, et al. Among authors: whittaker m. Comb Chem High Throughput Screen. 2007 May;10(4):261-7. doi: 10.2174/138620707780636592. Comb Chem High Throughput Screen. 2007. PMID: 17506709
Fragment-based identification of Hsp90 inhibitors.
Barker JJ, Barker O, Boggio R, Chauhan V, Cheng RK, Corden V, Courtney SM, Edwards N, Falque VM, Fusar F, Gardiner M, Hamelin EM, Hesterkamp T, Ichihara O, Jones RS, Mather O, Mercurio C, Minucci S, Montalbetti CA, Müller A, Patel D, Phillips BG, Varasi M, Whittaker M, Winkler D, Yarnold CJ. Barker JJ, et al. Among authors: whittaker m. ChemMedChem. 2009 Jun;4(6):963-6. doi: 10.1002/cmdc.200900011. ChemMedChem. 2009. PMID: 19301319
The multiple roles of computational chemistry in fragment-based drug design.
Law R, Barker O, Barker JJ, Hesterkamp T, Godemann R, Andersen O, Fryatt T, Courtney S, Hallett D, Whittaker M. Law R, et al. Among authors: whittaker m. J Comput Aided Mol Des. 2009 Aug;23(8):459-73. doi: 10.1007/s10822-009-9284-1. Epub 2009 Jun 17. J Comput Aided Mol Des. 2009. PMID: 19533374
Novel MK2 inhibitors by fragment screening.
Keminer O, Kraemer J, Kahmann J, Sternberger I, Scheich C, Jungmann J, Schaert S, Winkler D, Ichihara O, Whittaker M, Ullmann D, Hesterkamp T. Keminer O, et al. Among authors: whittaker m. Comb Chem High Throughput Screen. 2009 Aug;12(7):697-703. doi: 10.2174/138620709788923700. Epub 2009 Aug 1. Comb Chem High Throughput Screen. 2009. PMID: 19531016
Discovery of a novel Hsp90 inhibitor by fragment linking.
Barker JJ, Barker O, Courtney SM, Gardiner M, Hesterkamp T, Ichihara O, Mather O, Montalbetti CA, Müller A, Varasi M, Whittaker M, Yarnold CJ. Barker JJ, et al. Among authors: whittaker m. ChemMedChem. 2010 Oct 4;5(10):1697-700. doi: 10.1002/cmdc.201000219. ChemMedChem. 2010. PMID: 20665758 No abstract available.
571 results