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The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates.
Krivokrysenko VI, Toshkov IA, Gleiberman AS, Krasnov P, Shyshynova I, Bespalov I, Maitra RK, Narizhneva NV, Singh VK, Whitnall MH, Purmal AA, Shakhov AN, Gudkov AV, Feinstein E. Krivokrysenko VI, et al. Among authors: whitnall mh. PLoS One. 2015 Sep 14;10(9):e0135388. doi: 10.1371/journal.pone.0135388. eCollection 2015. PLoS One. 2015. PMID: 26367124 Free PMC article.
Accelerated hematopoietic syndrome after radiation doses bridging hematopoietic (H-ARS) and gastrointestinal (GI-ARS) acute radiation syndrome: early hematological changes and systemic inflammatory response syndrome in minipig.
Moroni M, Elliott TB, Deutz NE, Olsen CH, Owens R, Christensen C, Lombardini ED, Whitnall MH. Moroni M, et al. Among authors: whitnall mh. Int J Radiat Biol. 2014 May;90(5):363-72. doi: 10.3109/09553002.2014.892226. Int J Radiat Biol. 2014. PMID: 24524283
The Gottingen minipig is a model of the hematopoietic acute radiation syndrome: G-colony stimulating factor stimulates hematopoiesis and enhances survival from lethal total-body γ-irradiation.
Moroni M, Ngudiankama BF, Christensen C, Olsen CH, Owens R, Lombardini ED, Holt RK, Whitnall MH. Moroni M, et al. Among authors: whitnall mh. Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):986-92. doi: 10.1016/j.ijrobp.2013.04.041. Int J Radiat Oncol Biol Phys. 2013. PMID: 23845847 Free PMC article.
5-AED enhances survival of irradiated mice in a G-CSF-dependent manner, stimulates innate immune cell function, reduces radiation-induced DNA damage and induces genes that modulate cell cycle progression and apoptosis.
Grace MB, Singh VK, Rhee JG, Jackson WE 3rd, Kao TC, Whitnall MH. Grace MB, et al. Among authors: whitnall mh. J Radiat Res. 2012 Nov 1;53(6):840-53. doi: 10.1093/jrr/rrs060. Epub 2012 Jul 22. J Radiat Res. 2012. PMID: 22843381 Free PMC article.
82 results