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Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.
Nat Cancer. 2021 Feb;2(2):157-173. doi: 10.1038/s43018-020-00154-9. Epub 2021 Jan 4.
Nat Cancer. 2021.
PMID: 35122077
Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor.
Selvadurai HJ, Luis E, Desai K, Lan X, Vladoiu MC, Whitley O, Galvin C, Vanner RJ, Lee L, Whetstone H, Kushida M, Nowakowski T, Diamandis P, Hawkins C, Bader G, Kriegstein A, Taylor MD, Dirks PB.
Selvadurai HJ, et al.
Cell Rep. 2020 Apr 14;31(2):107511. doi: 10.1016/j.celrep.2020.03.075.
Cell Rep. 2020.
PMID: 32294450
Free article.
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Wnt activation as a therapeutic strategy in medulloblastoma.
Manoranjan B, Venugopal C, Bakhshinyan D, Adile AA, Richards L, Kameda-Smith MM, Whitley O, Dvorkin-Gheva A, Subapanditha M, Savage N, Tatari N, McKenna D, Bassey-Archibong B, Winegarden N, Hallett R, Provias JP, Yarascavitch B, Ajani O, Fleming A, Bader GD, Pugh TJ, Doble BW, Singh SK.
Manoranjan B, et al.
Nat Commun. 2020 Aug 28;11(1):4323. doi: 10.1038/s41467-020-17953-4.
Nat Commun. 2020.
PMID: 32859895
Free PMC article.
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PRMT5 inhibition disrupts splicing and stemness in glioblastoma.
Sachamitr P, Ho JC, Ciamponi FE, Ba-Alawi W, Coutinho FJ, Guilhamon P, Kushida MM, Cavalli FMG, Lee L, Rastegar N, Vu V, Sánchez-Osuna M, Coulombe-Huntington J, Kanshin E, Whetstone H, Durand M, Thibault P, Hart K, Mangos M, Veyhl J, Chen W, Tran N, Duong BC, Aman AM, Che X, Lan X, Whitley O, Zaslaver O, Barsyte-Lovejoy D, Richards LM, Restall I, Caudy A, Röst HL, Bonday ZQ, Bernstein M, Das S, Cusimano MD, Spears J, Bader GD, Pugh TJ, Tyers M, Lupien M, Haibe-Kains B, Artee Luchman H, Weiss S, Massirer KB, Prinos P, Arrowsmith CH, Dirks PB.
Sachamitr P, et al.
Nat Commun. 2021 Feb 12;12(1):979. doi: 10.1038/s41467-021-21204-5.
Nat Commun. 2021.
PMID: 33579912
Free PMC article.
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Multi-scale systems genomics analysis predicts pathways, cell types, and drug targets involved in normative variation in peri-adolescent human cognition.
Pai S, Hui S, Weber P, Narayan S, Whitley O, Li P, Labrie V, Baumbach J, Wheeler AL, Bader GD.
Pai S, et al.
Cereb Cortex. 2023 Jun 20;33(13):8581-8593. doi: 10.1093/cercor/bhad142.
Cereb Cortex. 2023.
PMID: 37106565
Free PMC article.
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