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The calcium-sensing receptor: a novel Alzheimer's disease crucial target?
Armato U, Bonafini C, Chakravarthy B, Pacchiana R, Chiarini A, Whitfield JF, Dal Prà I. Armato U, et al. Among authors: whitfield jf. J Neurol Sci. 2012 Nov 15;322(1-2):137-40. doi: 10.1016/j.jns.2012.07.031. Epub 2012 Jul 28. J Neurol Sci. 2012. PMID: 22841885 Review.
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25-35 in human cortical astrocytes and neurons-therapeutic relevance to Alzheimer's disease.
Armato U, Chiarini A, Chakravarthy B, Chioffi F, Pacchiana R, Colarusso E, Whitfield JF, Dal Prà I. Armato U, et al. Among authors: whitfield jf. Biochim Biophys Acta. 2013 Oct;1832(10):1634-52. doi: 10.1016/j.bbadis.2013.04.020. Epub 2013 Apr 26. Biochim Biophys Acta. 2013. PMID: 23628734 Free article.
371 results