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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.
Nelvagal HR, Eaton SL, Wang SH, Eultgen EM, Takahashi K, Le SQ, Nesbitt R, Dearborn JT, Siano N, Puhl AC, Dickson PI, Thompson G, Murdoch F, Brennan PM, Gray M, Greenhalgh SN, Tennant P, Gregson R, Clutton E, Nixon J, Proudfoot C, Guido S, Lillico SG, Whitelaw CBA, Lu JY, Hofmann SL, Ekins S, Sands MS, Wishart TM, Cooper JD. Nelvagal HR, et al. Among authors: whitelaw cba. J Clin Invest. 2022 Oct 17;132(20):e163107. doi: 10.1172/JCI163107. J Clin Invest. 2022. PMID: 36040802 Free PMC article.
Transgenic sheep designed for transplantation studies.
Ritchie WA, King T, Neil C, Carlisle AJ, Lillico S, McLachlan G, Whitelaw CB. Ritchie WA, et al. Mol Reprod Dev. 2009 Jan;76(1):61-4. doi: 10.1002/mrd.20930. Mol Reprod Dev. 2009. PMID: 18449866
Efficient TALEN-mediated gene knockout in livestock.
Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, Christian M, Voytas DF, Long CR, Whitelaw CB, Fahrenkrug SC. Carlson DF, et al. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17382-7. doi: 10.1073/pnas.1211446109. Epub 2012 Oct 1. Proc Natl Acad Sci U S A. 2012. PMID: 23027955 Free PMC article.
Live pigs produced from genome edited zygotes.
Lillico SG, Proudfoot C, Carlson DF, Stverakova D, Neil C, Blain C, King TJ, Ritchie WA, Tan W, Mileham AJ, McLaren DG, Fahrenkrug SC, Whitelaw CB. Lillico SG, et al. Sci Rep. 2013 Oct 10;3:2847. doi: 10.1038/srep02847. Sci Rep. 2013. PMID: 24108318 Free PMC article.
Genome edited sheep and cattle.
Proudfoot C, Carlson DF, Huddart R, Long CR, Pryor JH, King TJ, Lillico SG, Mileham AJ, McLaren DG, Whitelaw CB, Fahrenkrug SC. Proudfoot C, et al. Transgenic Res. 2015 Feb;24(1):147-53. doi: 10.1007/s11248-014-9832-x. Epub 2014 Sep 10. Transgenic Res. 2015. PMID: 25204701 Free PMC article.
Engineering large animal models of human disease.
Whitelaw CB, Sheets TP, Lillico SG, Telugu BP. Whitelaw CB, et al. J Pathol. 2016 Jan;238(2):247-56. doi: 10.1002/path.4648. Epub 2015 Nov 28. J Pathol. 2016. PMID: 26414877 Free PMC article. Review.
84 results