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Efficient TALEN-mediated gene knockout in livestock.
Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, Christian M, Voytas DF, Long CR, Whitelaw CB, Fahrenkrug SC. Carlson DF, et al. Among authors: whitelaw cb. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17382-7. doi: 10.1073/pnas.1211446109. Epub 2012 Oct 1. Proc Natl Acad Sci U S A. 2012. PMID: 23027955 Free PMC article.
Transgenic sheep designed for transplantation studies.
Ritchie WA, King T, Neil C, Carlisle AJ, Lillico S, McLachlan G, Whitelaw CB. Ritchie WA, et al. Among authors: whitelaw cb. Mol Reprod Dev. 2009 Jan;76(1):61-4. doi: 10.1002/mrd.20930. Mol Reprod Dev. 2009. PMID: 18449866
Ovine-induced pluripotent stem cells can contribute to chimeric lambs.
Sartori C, DiDomenico AI, Thomson AJ, Milne E, Lillico SG, Burdon TG, Whitelaw CB. Sartori C, et al. Among authors: whitelaw cb. Cell Reprogram. 2012 Feb;14(1):8-19. doi: 10.1089/cell.2011.0050. Epub 2012 Jan 4. Cell Reprogram. 2012. PMID: 22217199
Live pigs produced from genome edited zygotes.
Lillico SG, Proudfoot C, Carlson DF, Stverakova D, Neil C, Blain C, King TJ, Ritchie WA, Tan W, Mileham AJ, McLaren DG, Fahrenkrug SC, Whitelaw CB. Lillico SG, et al. Among authors: whitelaw cb. Sci Rep. 2013 Oct 10;3:2847. doi: 10.1038/srep02847. Sci Rep. 2013. PMID: 24108318 Free PMC article.
Genome edited sheep and cattle.
Proudfoot C, Carlson DF, Huddart R, Long CR, Pryor JH, King TJ, Lillico SG, Mileham AJ, McLaren DG, Whitelaw CB, Fahrenkrug SC. Proudfoot C, et al. Among authors: whitelaw cb. Transgenic Res. 2015 Feb;24(1):147-53. doi: 10.1007/s11248-014-9832-x. Epub 2014 Sep 10. Transgenic Res. 2015. PMID: 25204701 Free PMC article.
Highly efficient targeted chromosome deletions using CRISPR/Cas9.
He Z, Proudfoot C, Mileham AJ, McLaren DG, Whitelaw CB, Lillico SG. He Z, et al. Among authors: whitelaw cb. Biotechnol Bioeng. 2015 May;112(5):1060-4. doi: 10.1002/bit.25490. Epub 2014 Dec 23. Biotechnol Bioeng. 2015. PMID: 25362885
Engineering large animal models of human disease.
Whitelaw CB, Sheets TP, Lillico SG, Telugu BP. Whitelaw CB, et al. J Pathol. 2016 Jan;238(2):247-56. doi: 10.1002/path.4648. Epub 2015 Nov 28. J Pathol. 2016. PMID: 26414877 Free PMC article. Review.
116 results