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Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation.
Sci Rep. 2018 May 8;8(1):7108. doi: 10.1038/s41598-018-25487-5.
Sci Rep. 2018.
PMID: 29740032
Free PMC article.
Identification of the Binding Sites on Rab5 and p110beta Phosphatidylinositol 3-kinase.
Whitecross DE, Anderson DH.
Whitecross DE, et al.
Sci Rep. 2017 Nov 23;7(1):16194. doi: 10.1038/s41598-017-16029-6.
Sci Rep. 2017.
PMID: 29170408
Free PMC article.
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Impact of p85α Alterations in Cancer.
Marshall JDS, Whitecross DE, Mellor P, Anderson DH.
Marshall JDS, et al. Among authors: whitecross de.
Biomolecules. 2019 Jan 15;9(1):29. doi: 10.3390/biom9010029.
Biomolecules. 2019.
PMID: 30650664
Free PMC article.
Review.
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Insight into the PTEN - p85α interaction and lipid binding properties of the p85α BH domain.
Marshall JDS, Mellor P, Ruan X, Whitecross DE, Moore SA, Anderson DH.
Marshall JDS, et al. Among authors: whitecross de.
Oncotarget. 2018 Dec 11;9(97):36975-36992. doi: 10.18632/oncotarget.26432. eCollection 2018 Dec 11.
Oncotarget. 2018.
PMID: 30651929
Free PMC article.
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