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Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.
Banerjee A, Herring CA, Chen B, Kim H, Simmons AJ, Southard-Smith AN, Allaman MM, White JR, Macedonia MC, Mckinley ET, Ramirez-Solano MA, Scoville EA, Liu Q, Wilson KT, Coffey RJ, Washington MK, Goettel JA, Lau KS. Banerjee A, et al. Among authors: white jr. Gastroenterology. 2020 Dec;159(6):2101-2115.e5. doi: 10.1053/j.gastro.2020.08.029. Epub 2020 Aug 21. Gastroenterology. 2020. PMID: 32828819 Free PMC article.
A Central Role for Lipocalin-2 in the Adaptation to Short-Bowel Syndrome Through Down-Regulation of IL22 in Mice.
Zhang A, Sodhi CP, Wang M, Shores DR, Fulton W, Prindle T, Brosten S, O'Hare E, Lau A, Ding H, Jia H, Lu P, White JR, Hui J, Sears CL, Hackam DJ, Alaish SM. Zhang A, et al. Among authors: white jr. Cell Mol Gastroenterol Hepatol. 2020;10(2):309-326. doi: 10.1016/j.jcmgh.2020.04.006. Epub 2020 Apr 21. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32330729 Free PMC article.
Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice.
Drewes JL, Chen J, Markham NO, Knippel RJ, Domingue JC, Tam AJ, Chan JL, Kim L, McMann M, Stevens C, Dejea CM, Tomkovich S, Michel J, White JR, Mohammad F, Campodónico VL, Heiser CN, Wu X, Wu S, Ding H, Simner P, Carroll K, Shrubsole MJ, Anders RA, Walk ST, Jobin C, Wan F, Coffey RJ, Housseau F, Lau KS, Sears CL. Drewes JL, et al. Among authors: white jr. Cancer Discov. 2022 Aug 5;12(8):1873-1885. doi: 10.1158/2159-8290.CD-21-1273. Cancer Discov. 2022. PMID: 35678528 Free PMC article.
Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
Tomkovich S, Dejea CM, Winglee K, Drewes JL, Chung L, Housseau F, Pope JL, Gauthier J, Sun X, Mühlbauer M, Liu X, Fathi P, Anders RA, Besharati S, Perez-Chanona E, Yang Y, Ding H, Wu X, Wu S, White JR, Gharaibeh RZ, Fodor AA, Wang H, Pardoll DM, Jobin C, Sears CL. Tomkovich S, et al. Among authors: white jr. J Clin Invest. 2019 Mar 11;129(4):1699-1712. doi: 10.1172/JCI124196. eCollection 2019 Mar 11. J Clin Invest. 2019. PMID: 30855275 Free PMC article.
Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes.
Riquelme E, Zhang Y, Zhang L, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A, Scheet P, Xu H, Hanash SM, Feng L, Burks JK, Do KA, Peterson CB, Nejman D, Tzeng CD, Kim MP, Sears CL, Ajami N, Petrosino J, Wood LD, Maitra A, Straussman R, Katz M, White JR, Jenq R, Wargo J, McAllister F. Riquelme E, et al. Among authors: white jr. Cell. 2019 Aug 8;178(4):795-806.e12. doi: 10.1016/j.cell.2019.07.008. Cell. 2019. PMID: 31398337 Free PMC article.
Composition of gastrointestinal microbiota in association with treatment response in individuals with metastatic castrate resistant prostate cancer progressing on enzalutamide and initiating treatment with anti-PD-1 (pembrolizumab).
Peiffer LB, White JR, Jones CB, Slottke RE, Ernst SE, Moran AE, Graff JN, Sfanos KS. Peiffer LB, et al. Among authors: white jr. Neoplasia. 2022 Oct;32:100822. doi: 10.1016/j.neo.2022.100822. Epub 2022 Jul 28. Neoplasia. 2022. PMID: 35908379 Free PMC article.
Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants.
Sellitto M, Bai G, Serena G, Fricke WF, Sturgeon C, Gajer P, White JR, Koenig SS, Sakamoto J, Boothe D, Gicquelais R, Kryszak D, Puppa E, Catassi C, Ravel J, Fasano A. Sellitto M, et al. Among authors: white jr. PLoS One. 2012;7(3):e33387. doi: 10.1371/journal.pone.0033387. Epub 2012 Mar 14. PLoS One. 2012. PMID: 22432018 Free PMC article. Clinical Trial.
Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors.
Shaikh FY, Gills JJ, Mohammad F, White JR, Stevens CM, Ding H, Fu J, Tam A, Blosser RL, Domingue JC, Larman TC, Chaft JE, Spicer JD, Reuss JE, Naidoo J, Forde PM, Ganguly S, Housseau F, Pardoll DM, Sears CL. Shaikh FY, et al. Among authors: white jr. Cancer Immunol Immunother. 2022 Oct;71(10):2405-2420. doi: 10.1007/s00262-022-03169-6. Epub 2022 Feb 26. Cancer Immunol Immunother. 2022. PMID: 35217892 Free PMC article.
2,008 results