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Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals.
Lederer K, Bettini E, Parvathaneni K, Painter MM, Agarwal D, Lundgreen KA, Weirick M, Muralidharan K, Castaño D, Goel RR, Xu X, Drapeau EM, Gouma S, Ort JT, Awofolaju M, Greenplate AR, Le Coz C, Romberg N, Trofe-Clark J, Malat G, Jones L, Rosen M, Weiskopf D, Sette A, Besharatian B, Kaminiski M, Hensley SE, Bates P, Wherry EJ, Naji A, Bhoj V, Locci M. Lederer K, et al. Among authors: wherry ej. Cell. 2022 Mar 17;185(6):1008-1024.e15. doi: 10.1016/j.cell.2022.01.027. Epub 2022 Feb 2. Cell. 2022. PMID: 35202565 Free PMC article.
Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.
Naradikian MS, Myles A, Beiting DP, Roberts KJ, Dawson L, Herati RS, Bengsch B, Linderman SL, Stelekati E, Spolski R, Wherry EJ, Hunter C, Hensley SE, Leonard WJ, Cancro MP. Naradikian MS, et al. Among authors: wherry ej. J Immunol. 2016 Aug 15;197(4):1023-8. doi: 10.4049/jimmunol.1600522. Epub 2016 Jul 18. J Immunol. 2016. PMID: 27430719 Free PMC article.
Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells.
Herati RS, Muselman A, Vella L, Bengsch B, Parkhouse K, Del Alcazar D, Kotzin J, Doyle SA, Tebas P, Hensley SE, Su LF, Schmader KE, Wherry EJ. Herati RS, et al. Among authors: wherry ej. Sci Immunol. 2017 Feb;2(8):eaag2152. doi: 10.1126/sciimmunol.aag2152. Epub 2017 Feb 17. Sci Immunol. 2017. PMID: 28620653 Free PMC article.
Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage.
Le Coz C, Bengsch B, Khanna C, Trofa M, Ohtani T, Nolan BE, Henrickson SE, Lambert MP, Kim TO, Despotovic JM, Feldman S, Fadugba OO, Takach P, Ruffner M, Jyonouchi S, Heimall J, Sullivan KE, Wherry EJ, Romberg N. Le Coz C, et al. Among authors: wherry ej. J Allergy Clin Immunol. 2019 Dec;144(6):1660-1673. doi: 10.1016/j.jaci.2019.08.007. Epub 2019 Aug 22. J Allergy Clin Immunol. 2019. PMID: 31445098 Free PMC article. Clinical Trial.
The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans.
Johnson JL, Rosenthal RL, Knox JJ, Myles A, Naradikian MS, Madej J, Kostiv M, Rosenfeld AM, Meng W, Christensen SR, Hensley SE, Yewdell J, Canaday DH, Zhu J, McDermott AB, Dori Y, Itkin M, Wherry EJ, Pardi N, Weissman D, Naji A, Prak ETL, Betts MR, Cancro MP. Johnson JL, et al. Among authors: wherry ej. Immunity. 2020 May 19;52(5):842-855.e6. doi: 10.1016/j.immuni.2020.03.020. Epub 2020 Apr 29. Immunity. 2020. PMID: 32353250 Free PMC article.
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions.
Mathew D, Giles JR, Baxter AE, Greenplate AR, Wu JE, Alanio C, Oldridge DA, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Hensley SE, Apostolidis S, Huang AC, Vella LA; UPenn COVID Processing Unit; Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2020 May 23:2020.05.20.106401. doi: 10.1101/2020.05.20.106401. bioRxiv. 2020. PMID: 32511371 Free PMC article. Updated. Preprint.
Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum R, Mathew D, Baxter AE, Vella L, Kuthuru O, Apostolidis S, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. Among authors: wherry ej. bioRxiv [Preprint]. 2020 May 18:2020.05.18.101717. doi: 10.1101/2020.05.18.101717. bioRxiv. 2020. PMID: 32511394 Free PMC article. Preprint.
341 results