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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.
Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Carette JE, et al. Among authors: whelan sp. Nature. 2011 Aug 24;477(7364):340-3. doi: 10.1038/nature10348. Nature. 2011. PMID: 21866103 Free PMC article.
Ebola virus entry requires the host-programmed recognition of an intracellular receptor.
Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. Miller EH, et al. Among authors: whelan sp. EMBO J. 2012 Apr 18;31(8):1947-60. doi: 10.1038/emboj.2012.53. Epub 2012 Mar 6. EMBO J. 2012. PMID: 22395071 Free PMC article.
Virus entry. Lassa virus entry requires a trigger-induced receptor switch.
Jae LT, Raaben M, Herbert AS, Kuehne AI, Wirchnianski AS, Soh TK, Stubbs SH, Janssen H, Damme M, Saftig P, Whelan SP, Dye JM, Brummelkamp TR. Jae LT, et al. Among authors: whelan sp. Science. 2014 Jun 27;344(6191):1506-10. doi: 10.1126/science.1252480. Science. 2014. PMID: 24970085 Free PMC article.
Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.
Herbert AS, Davidson C, Kuehne AI, Bakken R, Braigen SZ, Gunn KE, Whelan SP, Brummelkamp TR, Twenhafel NA, Chandran K, Walkley SU, Dye JM. Herbert AS, et al. Among authors: whelan sp. mBio. 2015 May 26;6(3):e00565-15. doi: 10.1128/mBio.00565-15. mBio. 2015. PMID: 26015498 Free PMC article.
A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles.
Ndungo E, Herbert AS, Raaben M, Obernosterer G, Biswas R, Miller EH, Wirchnianski AS, Carette JE, Brummelkamp TR, Whelan SP, Dye JM, Chandran K. Ndungo E, et al. Among authors: whelan sp. mSphere. 2016 Mar 30;1(2):e00007-16. doi: 10.1128/mSphere.00007-16. eCollection 2016 Mar-Apr. mSphere. 2016. PMID: 27303731 Free PMC article.
172 results