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A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Guo Q, Xin M, Lu Q, Feng D, Yang V, Peng LF, Whelan KA, Hu W, Wu S, Yang X, Wang H, Rothberg BS, Gamero AM, Gerhard GS, Gao B, Yang L. Guo Q, et al. Among authors: whelan ka. Theranostics. 2023 Apr 9;13(7):2210-2225. doi: 10.7150/thno.81192. eCollection 2023. Theranostics. 2023. PMID: 37153733 Free PMC article.
Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes.
Chandramouleeswaran PM, Guha M, Shimonosono M, Whelan KA, Maekawa H, Sachdeva UM, Ruthel G, Mukherjee S, Engel N, Gonzalez MV, Garifallou J, Ohashi S, Klein-Szanto AJ, Mesaros CA, Blair IA, Pellegrino da Silva R, Hakonarson H, Noguchi E, Baur JA, Nakagawa H. Chandramouleeswaran PM, et al. Among authors: whelan ka. PLoS One. 2020 Sep 23;15(9):e0239625. doi: 10.1371/journal.pone.0239625. eCollection 2020. PLoS One. 2020. PMID: 32966340 Free PMC article.
Intestinal epithelial autophagy is required for the regenerative benefit of calorie restriction.
Williams PA, Naughton KE, Simon LA, Soto GE, Parham LR, Ma X, Danan CH, Hu W, Friedman ES, McMillan EA, Mehta H, Stoltz MA, Ocaña JS, Zackular JP, Bittinger K, Whelan KA, Karakasheva TA, Hamilton KE. Williams PA, et al. Among authors: whelan ka. Am J Physiol Gastrointest Liver Physiol. 2023 May 1;324(5):G354-G368. doi: 10.1152/ajpgi.00248.2022. Epub 2023 Feb 28. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36852920 Free PMC article.
Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis.
Sasaki M, Hara T, Wang JX, Zhou Y, Kennedy KV, Umeweni NN, Alston MA, Spergel ZC, Nakagawa R, Mcmillan EA, Whelan KA, Karakasheva TA, Hamilton KE, Ruffner MA, Muir AB. Sasaki M, et al. Among authors: whelan ka. bioRxiv [Preprint]. 2023 Mar 28:2023.03.27.534387. doi: 10.1101/2023.03.27.534387. bioRxiv. 2023. PMID: 37034590 Free PMC article. Updated. Preprint.
Lysyl Oxidase Regulates Epithelial Differentiation and Barrier Integrity in Eosinophilic Esophagitis.
Sasaki M, Hara T, Wang JX, Zhou Y, Kennedy KV, Umeweni CN, Alston MA, Spergel ZC, Ishikawa S, Teranishi R, Nakagawa R, Mcmillan EA, Whelan KA, Karakasheva TA, Hamilton KE, Ruffner MA, Muir AB. Sasaki M, et al. Among authors: whelan ka. Cell Mol Gastroenterol Hepatol. 2024 Feb 9;17(6):923-937. doi: 10.1016/j.jcmgh.2024.01.025. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38340809 Free PMC article.
Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes.
Kelsen JR, Dawany N, Conrad MA, Karakasheva TA, Maurer K, Wei JM, Uman S, Dent MH, Behera R, Bryant LM, Ma X, Moreira L, Chatterji P, Shraim R, Merz A, Mizuno R, Simon LA, Muir AB, Giraudo C, Behrens EM, Whelan KA, Devoto M, Russo PA, Andres SF, Sullivan KE, Hamilton KE. Kelsen JR, et al. Among authors: whelan ka. Inflamm Bowel Dis. 2021 Jan 19;27(2):256-267. doi: 10.1093/ibd/izaa145. Inflamm Bowel Dis. 2021. PMID: 32556182 Free PMC article.
71 results