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RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways.
Gudiño V, Pohl SÖ, Billard CV, Cammareri P, Bolado A, Aitken S, Stevenson D, Hall AE, Agostino M, Cassidy J, Nixon C, von Kriegsheim A, Freile P, Popplewell L, Dickson G, Murphy L, Wheeler A, Dunlop M, Din F, Strathdee D, Sansom OJ, Myant KB. Gudiño V, et al. Among authors: wheeler a. Nat Commun. 2021 Apr 20;12(1):2335. doi: 10.1038/s41467-021-22531-3. Nat Commun. 2021. PMID: 33879799 Free PMC article.
Mena regulates nesprin-2 to control actin-nuclear lamina associations, trans-nuclear membrane signalling and gene expression.
Li Mow Chee F, Beernaert B, Griffith BGC, Loftus AEP, Kumar Y, Wills JC, Lee M, Valli J, Wheeler AP, Armstrong JD, Parsons M, Leigh IM, Proby CM, von Kriegsheim A, Bickmore WA, Frame MC, Byron A. Li Mow Chee F, et al. Among authors: wheeler ap. Nat Commun. 2023 Mar 23;14(1):1602. doi: 10.1038/s41467-023-37021-x. Nat Commun. 2023. PMID: 36959177 Free PMC article.
Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.
Riley JS, Quarato G, Cloix C, Lopez J, O'Prey J, Pearson M, Chapman J, Sesaki H, Carlin LM, Passos JF, Wheeler AP, Oberst A, Ryan KM, Tait SW. Riley JS, et al. Among authors: wheeler ap. EMBO J. 2018 Sep 3;37(17):e99238. doi: 10.15252/embj.201899238. Epub 2018 Jul 26. EMBO J. 2018. PMID: 30049712 Free PMC article.
DNMT3B PWWP mutations cause hypermethylation of heterochromatin.
Taglini F, Kafetzopoulos I, Rolls W, Musialik KI, Lee HY, Zhang Y, Marenda M, Kerr L, Finan H, Rubio-Ramon C, Gautier P, Wapenaar H, Kumar D, Davidson-Smith H, Wills J, Murphy LC, Wheeler A, Wilson MD, Sproul D. Taglini F, et al. Among authors: wheeler a. EMBO Rep. 2024 Mar;25(3):1130-1155. doi: 10.1038/s44319-024-00061-5. Epub 2024 Jan 30. EMBO Rep. 2024. PMID: 38291337 Free PMC article.
1,259 results