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Small-molecule WNK inhibition regulates cardiovascular and renal function.
Yamada K, Park HM, Rigel DF, DiPetrillo K, Whalen EJ, Anisowicz A, Beil M, Berstler J, Brocklehurst CE, Burdick DA, Caplan SL, Capparelli MP, Chen G, Chen W, Dale B, Deng L, Fu F, Hamamatsu N, Harasaki K, Herr T, Hoffmann P, Hu QY, Huang WJ, Idamakanti N, Imase H, Iwaki Y, Jain M, Jeyaseelan J, Kato M, Kaushik VK, Kohls D, Kunjathoor V, LaSala D, Lee J, Liu J, Luo Y, Ma F, Mo R, Mowbray S, Mogi M, Ossola F, Pandey P, Patel SJ, Raghavan S, Salem B, Shanado YH, Trakshel GM, Turner G, Wakai H, Wang C, Weldon S, Wielicki JB, Xie X, Xu L, Yagi YI, Yasoshima K, Yin J, Yowe D, Zhang JH, Zheng G, Monovich L. Yamada K, et al. Among authors: whalen ej. Nat Chem Biol. 2016 Nov;12(11):896-898. doi: 10.1038/nchembio.2168. Epub 2016 Sep 5. Nat Chem Biol. 2016. PMID: 27595330
beta-arrestin-biased agonism at the beta2-adrenergic receptor.
Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ. Drake MT, et al. Among authors: whalen ej. J Biol Chem. 2008 Feb 29;283(9):5669-76. doi: 10.1074/jbc.M708118200. Epub 2007 Dec 17. J Biol Chem. 2008. PMID: 18086673 Free article.
Beta-arrestin-mediated signaling regulates protein synthesis.
DeWire SM, Kim J, Whalen EJ, Ahn S, Chen M, Lefkowitz RJ. DeWire SM, et al. Among authors: whalen ej. J Biol Chem. 2008 Apr 18;283(16):10611-20. doi: 10.1074/jbc.M710515200. Epub 2008 Feb 14. J Biol Chem. 2008. PMID: 18276584 Free PMC article.
beta-arrestins: traffic cops of cell signaling.
Lefkowitz RJ, Whalen EJ. Lefkowitz RJ, et al. Among authors: whalen ej. Curr Opin Cell Biol. 2004 Apr;16(2):162-8. doi: 10.1016/j.ceb.2004.01.001. Curr Opin Cell Biol. 2004. PMID: 15196559 Review.
54 results