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Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen.
Nat Commun. 2022 Sep 10;13(1):5333. doi: 10.1038/s41467-022-32811-1.
Nat Commun. 2022.
PMID: 36088370
Free PMC article.
Functional characterization of a novel somatic oncogenic mutation of PIK3CB.
Whale AD, Colman L, Lensun L, Rogers HL, Shuttleworth SJ.
Whale AD, et al.
Signal Transduct Target Ther. 2017 Dec 22;2:17063. doi: 10.1038/sigtrans.2017.63. eCollection 2017.
Signal Transduct Target Ther. 2017.
PMID: 29279775
Free PMC article.
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PAK4 kinase activity and somatic mutation promote carcinoma cell motility and influence inhibitor sensitivity.
Whale AD, Dart A, Holt M, Jones GE, Wells CM.
Whale AD, et al.
Oncogene. 2013 Apr 18;32(16):2114-20. doi: 10.1038/onc.2012.233. Epub 2012 Jun 11.
Oncogene. 2013.
PMID: 22689056
Free PMC article.
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PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion.
Wells CM, Whale AD, Parsons M, Masters JR, Jones GE.
Wells CM, et al. Among authors: whale ad.
J Cell Sci. 2010 May 15;123(Pt 10):1663-73. doi: 10.1242/jcs.055707. Epub 2010 Apr 20.
J Cell Sci. 2010.
PMID: 20406887
Free PMC article.
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Cortactin recruitment by enterohemorrhagic Escherichia coli O157:H7 during infection in vitro and ex vivo.
Mousnier A, Whale AD, Schüller S, Leong JM, Phillips AD, Frankel G.
Mousnier A, et al. Among authors: whale ad.
Infect Immun. 2008 Oct;76(10):4669-76. doi: 10.1128/IAI.00140-08. Epub 2008 Aug 4.
Infect Immun. 2008.
PMID: 18678675
Free PMC article.
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TccP2-mediated subversion of actin dynamics by EPEC 2 - a distinct evolutionary lineage of enteropathogenic Escherichia coli.
Whale AD, Hernandes RT, Ooka T, Beutin L, Schüller S, Garmendia J, Crowther L, Vieira MAM, Ogura Y, Krause G, Phillips AD, Gomes TAT, Hayashi T, Frankel G.
Whale AD, et al.
Microbiology (Reading). 2007 Jun;153(Pt 6):1743-1755. doi: 10.1099/mic.0.2006/004325-0.
Microbiology (Reading). 2007.
PMID: 17526832
Free PMC article.
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A novel category of enteropathogenic Escherichia coli simultaneously utilizes the Nck and TccP pathways to induce actin remodelling.
Whale AD, Garmendia J, Gomes TA, Frankel G.
Whale AD, et al.
Cell Microbiol. 2006 Jun;8(6):999-1008. doi: 10.1111/j.1462-5822.2006.00682.x.
Cell Microbiol. 2006.
PMID: 16681840
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PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms.
Freeman DJ, Li AG, Wei G, Li HH, Kertesz N, Lesche R, Whale AD, Martinez-Diaz H, Rozengurt N, Cardiff RD, Liu X, Wu H.
Freeman DJ, et al. Among authors: whale ad.
Cancer Cell. 2003 Feb;3(2):117-30. doi: 10.1016/s1535-6108(03)00021-7.
Cancer Cell. 2003.
PMID: 12620407
Free article.
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