Weygant N - Search Results

1

The role of sex in the innate and adaptive immune environment of metastatic colorectal cancer.

Ray AL, Nofchissey RA, Khan MA, Reidy MA, Lerner MR, Wu X, Guo S, Hill SL, Weygant N, Adams SF, Castillo EF, Berry WL, Stout MB, Morris KT. Ray AL, et al. Among authors: weygant n. Br J Cancer. 2020 Aug;123(4):624-632. doi: 10.1038/s41416-020-0913-8. Epub 2020 May 26. Br J Cancer. 2020. PMID: 32451467 Free PMC article.

2

Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.

Ali N, Allam H, Bader T, May R, Basalingappa KM, Berry WL, Chandrakesan P, Qu D, Weygant N, Bronze MS, Umar S, Janknecht R, Sureban SM, Huycke M, Houchen CW. Ali N, et al. Among authors: weygant n. PLoS One. 2013 Nov 19;8(11):e80304. doi: 10.1371/journal.pone.0080304. eCollection 2013. PLoS One. 2013. PMID: 24260365 Free PMC article.

3

Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.

Weygant N, Qu D, Berry WL, May R, Chandrakesan P, Owen DB, Sureban SM, Ali N, Janknecht R, Houchen CW. Weygant N, et al. Mol Cancer. 2014 May 6;13:103. doi: 10.1186/1476-4598-13-103. Mol Cancer. 2014. PMID: 24885928 Free PMC article.

4

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma.

Weygant N, Qu D, May R, Tierney RM, Berry WL, Zhao L, Agarwal S, Chandrakesan P, Chinthalapally HR, Murphy NT, Li JD, Sureban SM, Schlosser MJ, Tomasek JJ, Houchen CW. Weygant N, et al. Oncotarget. 2015 Feb 10;6(4):2193-205. doi: 10.18632/oncotarget.3059. Oncotarget. 2015. PMID: 25605241 Free PMC article.

5

Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases.

Ali N, Chandrakesan P, Nguyen CB, Husain S, Gillaspy AF, Huycke M, Berry WL, May R, Qu D, Weygant N, Sureban SM, Bronze MS, Dhanasekaran DN, Houchen CW. Ali N, et al. Among authors: weygant n. Oncotarget. 2015 Aug 21;6(24):20327-44. doi: 10.18632/oncotarget.3972. Oncotarget. 2015. PMID: 25948779 Free PMC article.

6

Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase.

Weygant N, Ge Y, Qu D, Kaddis JS, Berry WL, May R, Chandrakesan P, Bannerman-Menson E, Vega KJ, Tomasek JJ, Bronze MS, An G, Houchen CW. Weygant N, et al. Cancer Res. 2016 Jul 15;76(14):4090-9. doi: 10.1158/0008-5472.CAN-16-0029. Epub 2016 Jun 10. Cancer Res. 2016. PMID: 27287716 Free PMC article.

7

Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury.

Chandrakesan P, May R, Weygant N, Qu D, Berry WL, Sureban SM, Ali N, Rao C, Huycke M, Bronze MS, Houchen CW. Chandrakesan P, et al. Among authors: weygant n. Sci Rep. 2016 Nov 23;6:37667. doi: 10.1038/srep37667. Sci Rep. 2016. PMID: 27876863 Free PMC article.

8

Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.

Ge Y, Weygant N, Qu D, May R, Berry WL, Yao J, Chandrakesan P, Zheng W, Zhao L, Zhao KL, Drake M, Vega KJ, Bronze MS, Tomasek JJ, An G, Houchen CW. Ge Y, et al. Among authors: weygant n. Int J Cancer. 2018 Sep 1;143(5):1162-1175. doi: 10.1002/ijc.31400. Epub 2018 Apr 16. Int J Cancer. 2018. PMID: 29577277 Free PMC article.

9

Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer.

Qu D, Weygant N, Yao J, Chandrakesan P, Berry WL, May R, Pitts K, Husain S, Lightfoot S, Li M, Wang TC, An G, Clendenin C, Stanger BZ, Houchen CW. Qu D, et al. Among authors: weygant n. J Oncol. 2019 Aug 5;2019:6402925. doi: 10.1155/2019/6402925. eCollection 2019. J Oncol. 2019. PMID: 31467540 Free PMC article.

10

Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments.

Wu X, Qu D, Weygant N, Peng J, Houchen CW. Wu X, et al. Among authors: weygant n. Cancers (Basel). 2020 Jan 22;12(2):274. doi: 10.3390/cancers12020274. Cancers (Basel). 2020. PMID: 31979136 Free PMC article.

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