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ONC201/TIC10 Is Empowered by 2-Deoxyglucose and Causes Metabolic Reprogramming in Medulloblastoma Cells in Vitro Independent of C-Myc Expression.
Dwucet A, Pruss M, Cao Q, Tanriover M, Prabhu VV, Allen JE, Peraud A, Westhoff MA, Siegelin MD, Wirtz CR, Karpel-Massler G. Dwucet A, et al. Among authors: westhoff ma. Front Cell Dev Biol. 2021 Nov 26;9:734699. doi: 10.3389/fcell.2021.734699. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34900991 Free PMC article.
Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma.
Westhoff MA, Zhou S, Nonnenmacher L, Karpel-Massler G, Jennewein C, Schneider M, Halatsch ME, Carragher NO, Baumann B, Krause A, Simmet T, Bachem MG, Wirtz CR, Debatin KM. Westhoff MA, et al. Mol Cancer Res. 2013 Dec;11(12):1611-23. doi: 10.1158/1541-7786.MCR-13-0435-T. Epub 2013 Oct 21. Mol Cancer Res. 2013. PMID: 24145173
Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsy.
Lewerenz J, Baxter P, Kassubek R, Albrecht P, Van Liefferinge J, Westhoff MA, Halatsch ME, Karpel-Massler G, Meakin PJ, Hayes JD, Aronica E, Smolders I, Ludolph AC, Methner A, Conrad M, Massie A, Hardingham GE, Maher P. Lewerenz J, et al. Among authors: westhoff ma. Antioxid Redox Signal. 2014 Jun 20;20(18):2907-22. doi: 10.1089/ars.2013.5455. Epub 2014 Feb 6. Antioxid Redox Signal. 2014. PMID: 24219064 Free PMC article.
Killing me softly--future challenges in apoptosis research.
Westhoff MA, Brühl O, Nonnenmacher L, Karpel-Massler G, Debatin KM. Westhoff MA, et al. Int J Mol Sci. 2014 Mar 3;15(3):3746-67. doi: 10.3390/ijms15033746. Int J Mol Sci. 2014. PMID: 24595238 Free PMC article. Review.
RIST: a potent new combination therapy for glioblastoma.
Nonnenmacher L, Westhoff MA, Fulda S, Karpel-Massler G, Halatsch ME, Engelke J, Simmet T, Corbacioglu S, Debatin KM. Nonnenmacher L, et al. Among authors: westhoff ma. Int J Cancer. 2015 Feb 15;136(4):E173-87. doi: 10.1002/ijc.29138. Epub 2014 Sep 1. Int J Cancer. 2015. PMID: 25123598 Free article.
Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
Karpel-Massler G, Kast RE, Westhoff MA, Dwucet A, Welscher N, Nonnenmacher L, Hlavac M, Siegelin MD, Wirtz CR, Debatin KM, Halatsch ME. Karpel-Massler G, et al. Among authors: westhoff ma. J Neurooncol. 2015 Mar;122(1):21-33. doi: 10.1007/s11060-014-1688-7. Epub 2014 Dec 19. J Neurooncol. 2015. PMID: 25524815
PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma.
Karpel-Massler G, Pareja F, Aimé P, Shu C, Chau L, Westhoff MA, Halatsch ME, Crary JF, Canoll P, Siegelin MD. Karpel-Massler G, et al. Among authors: westhoff ma. PLoS One. 2014 Dec 22;9(12):e114583. doi: 10.1371/journal.pone.0114583. eCollection 2014. PLoS One. 2014. PMID: 25531448 Free PMC article.
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