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Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Fragki S, Dirven H, Fletcher T, Grasl-Kraupp B, Bjerve Gützkow K, Hoogenboom R, Kersten S, Lindeman B, Louisse J, Peijnenburg A, Piersma AH, Princen HMG, Uhl M, Westerhout J, Zeilmaker MJ, Luijten M. Fragki S, et al. Among authors: westerhout j. Crit Rev Toxicol. 2021 Feb;51(2):141-164. doi: 10.1080/10408444.2021.1888073. Epub 2021 Apr 15. Crit Rev Toxicol. 2021. PMID: 33853480 Review.
Evaluation of an alternative in vitro test battery for detecting reproductive toxicants.
Piersma AH, Bosgra S, van Duursen MB, Hermsen SA, Jonker LR, Kroese ED, van der Linden SC, Man H, Roelofs MJ, Schulpen SH, Schwarz M, Uibel F, van Vugt-Lussenburg BM, Westerhout J, Wolterbeek AP, van der Burg B. Piersma AH, et al. Among authors: westerhout j. Reprod Toxicol. 2013 Jul;38:53-64. doi: 10.1016/j.reprotox.2013.03.002. Epub 2013 Mar 16. Reprod Toxicol. 2013. PMID: 23511061
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Najjar A, Punt A, Wambaugh J, Paini A, Ellison C, Fragki S, Bianchi E, Zhang F, Westerhout J, Mueller D, Li H, Shi Q, Gant TW, Botham P, Bars R, Piersma A, van Ravenzwaay B, Kramer NI. Najjar A, et al. Among authors: westerhout j. Arch Toxicol. 2022 Dec;96(12):3407-3419. doi: 10.1007/s00204-022-03356-5. Epub 2022 Sep 5. Arch Toxicol. 2022. PMID: 36063173 Free PMC article.
Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics.
Wambaugh JF, Hughes MF, Ring CL, MacMillan DK, Ford J, Fennell TR, Black SR, Snyder RW, Sipes NS, Wetmore BA, Westerhout J, Setzer RW, Pearce RG, Simmons JE, Thomas RS. Wambaugh JF, et al. Among authors: westerhout j. Toxicol Sci. 2018 May 1;163(1):152-169. doi: 10.1093/toxsci/kfy020. Toxicol Sci. 2018. PMID: 29385628 Free PMC article.
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.
Zimmer B, Pallocca G, Dreser N, Foerster S, Waldmann T, Westerhout J, Julien S, Krause KH, van Thriel C, Hengstler JG, Sachinidis A, Bosgra S, Leist M. Zimmer B, et al. Among authors: westerhout j. Arch Toxicol. 2014 May;88(5):1109-26. doi: 10.1007/s00204-014-1231-9. Epub 2014 Apr 2. Arch Toxicol. 2014. PMID: 24691702 Free PMC article.
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Krug AK, Kolde R, Gaspar JA, Rempel E, Balmer NV, Meganathan K, Vojnits K, Baquié M, Waldmann T, Ensenat-Waser R, Jagtap S, Evans RM, Julien S, Peterson H, Zagoura D, Kadereit S, Gerhard D, Sotiriadou I, Heke M, Natarajan K, Henry M, Winkler J, Marchan R, Stoppini L, Bosgra S, Westerhout J, Verwei M, Vilo J, Kortenkamp A, Hescheler J, Hothorn L, Bremer S, van Thriel C, Krause KH, Hengstler JG, Rahnenführer J, Leist M, Sachinidis A. Krug AK, et al. Among authors: westerhout j. Arch Toxicol. 2013 Jan;87(1):123-43. doi: 10.1007/s00204-012-0967-3. Epub 2012 Nov 21. Arch Toxicol. 2013. PMID: 23179753 Free PMC article.
43 results