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Page 1
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ. Meerbrey KL, et al. Among authors: westbrook tf. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3665-70. doi: 10.1073/pnas.1019736108. Epub 2011 Feb 9. Proc Natl Acad Sci U S A. 2011. PMID: 21307310 Free PMC article.
A resource for large-scale RNA-interference-based screens in mammals.
Paddison PJ, Silva JM, Conklin DS, Schlabach M, Li M, Aruleba S, Balija V, O'Shaughnessy A, Gnoj L, Scobie K, Chang K, Westbrook T, Cleary M, Sachidanandam R, McCombie WR, Elledge SJ, Hannon GJ. Paddison PJ, et al. Nature. 2004 Mar 25;428(6981):427-31. doi: 10.1038/nature02370. Nature. 2004. PMID: 15042091
Dissecting cancer pathways and vulnerabilities with RNAi.
Westbrook TF, Stegmeier F, Elledge SJ. Westbrook TF, et al. Cold Spring Harb Symp Quant Biol. 2005;70:435-44. doi: 10.1101/sqb.2005.70.031. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869781 Review.
Cancer proliferation gene discovery through functional genomics.
Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ. Schlabach MR, et al. Among authors: westbrook tf. Science. 2008 Feb 1;319(5863):620-4. doi: 10.1126/science.1149200. Science. 2008. PMID: 18239126 Free PMC article.
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase.
Sun T, Aceto N, Meerbrey KL, Kessler JD, Zhou C, Migliaccio I, Nguyen DX, Pavlova NN, Botero M, Huang J, Bernardi RJ, Schmitt E, Hu G, Li MZ, Dephoure N, Gygi SP, Rao M, Creighton CJ, Hilsenbeck SG, Shaw CA, Muzny D, Gibbs RA, Wheeler DA, Osborne CK, Schiff R, Bentires-Alj M, Elledge SJ, Westbrook TF. Sun T, et al. Among authors: westbrook tf. Cell. 2011 Mar 4;144(5):703-18. doi: 10.1016/j.cell.2011.02.003. Cell. 2011. PMID: 21376233 Free PMC article.
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, Bernardi RJ, Yu B, Hsu T, Golding I, Luo J, Osborne CK, Creighton CJ, Hilsenbeck SG, Schiff R, Shaw CA, Elledge SJ, Westbrook TF. Kessler JD, et al. Among authors: westbrook tf. Science. 2012 Jan 20;335(6066):348-53. doi: 10.1126/science.1212728. Epub 2011 Dec 8. Science. 2012. PMID: 22157079 Free PMC article.
A role for PVRL4-driven cell-cell interactions in tumorigenesis.
Pavlova NN, Pallasch C, Elia AE, Braun CJ, Westbrook TF, Hemann M, Elledge SJ. Pavlova NN, et al. Among authors: westbrook tf. Elife. 2013 Apr 30;2:e00358. doi: 10.7554/eLife.00358. Elife. 2013. PMID: 23682311 Free PMC article.
59 results