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Biological properties of the PrP-like Shadoo protein.
Daude N, Westaway D. Daude N, et al. Among authors: westaway d. Front Biosci (Landmark Ed). 2011 Jan 1;16(4):1505-16. doi: 10.2741/3801. Front Biosci (Landmark Ed). 2011. PMID: 21196244 Free article. Review.
The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections.
Watts JC, Drisaldi B, Ng V, Yang J, Strome B, Horne P, Sy MS, Yoong L, Young R, Mastrangelo P, Bergeron C, Fraser PE, Carlson GA, Mount HT, Schmitt-Ulms G, Westaway D. Watts JC, et al. Among authors: westaway d. EMBO J. 2007 Sep 5;26(17):4038-50. doi: 10.1038/sj.emboj.7601830. Epub 2007 Aug 16. EMBO J. 2007. PMID: 17703189 Free PMC article.
Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones.
Watts JC, Huo H, Bai Y, Ehsani S, Jeon AH, Shi T, Daude N, Lau A, Young R, Xu L, Carlson GA, Williams D, Westaway D, Schmitt-Ulms G. Watts JC, et al. Among authors: westaway d. PLoS Pathog. 2009 Oct;5(10):e1000608. doi: 10.1371/journal.ppat.1000608. Epub 2009 Oct 2. PLoS Pathog. 2009. PMID: 19798432 Free PMC article.
Wild-type Shadoo proteins convert to amyloid-like forms under native conditions.
Daude N, Ng V, Watts JC, Genovesi S, Glaves JP, Wohlgemuth S, Schmitt-Ulms G, Young H, McLaurin J, Fraser PE, Westaway D. Daude N, et al. Among authors: westaway d. J Neurochem. 2010 Apr;113(1):92-104. doi: 10.1111/j.1471-4159.2010.06575.x. Epub 2010 Jan 8. J Neurochem. 2010. PMID: 20067571 Free article.
The PrP-like proteins Shadoo and Doppel.
Westaway D, Daude N, Wohlgemuth S, Harrison P. Westaway D, et al. Top Curr Chem. 2011;305:225-56. doi: 10.1007/128_2011_190. Top Curr Chem. 2011. PMID: 21728138 Review.
Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.
Westaway D, Genovesi S, Daude N, Brown R, Lau A, Lee I, Mays CE, Coomaraswamy J, Canine B, Pitstick R, Herbst A, Yang J, Ko KW, Schmitt-Ulms G, Dearmond SJ, McKenzie D, Hood L, Carlson GA. Westaway D, et al. PLoS Pathog. 2011 Nov;7(11):e1002391. doi: 10.1371/journal.ppat.1002391. Epub 2011 Nov 17. PLoS Pathog. 2011. PMID: 22114562 Free PMC article.
221 results