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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Hewitt G, et al. Among authors: west sc. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333017 Free PMC article.
Actions of aprataxin in multiple DNA repair pathways.
Rass U, Ahel I, West SC. Rass U, et al. Among authors: west sc. J Biol Chem. 2007 Mar 30;282(13):9469-9474. doi: 10.1074/jbc.M611489200. Epub 2007 Feb 2. J Biol Chem. 2007. PMID: 17276982 Free article.
Defective DNA repair and neurodegenerative disease.
Rass U, Ahel I, West SC. Rass U, et al. Among authors: west sc. Cell. 2007 Sep 21;130(6):991-1004. doi: 10.1016/j.cell.2007.08.043. Cell. 2007. PMID: 17889645 Free article. Review.
RTEL1 maintains genomic stability by suppressing homologous recombination.
Barber LJ, Youds JL, Ward JD, McIlwraith MJ, O'Neil NJ, Petalcorin MI, Martin JS, Collis SJ, Cantor SB, Auclair M, Tissenbaum H, West SC, Rose AM, Boulton SJ. Barber LJ, et al. Among authors: west sc. Cell. 2008 Oct 17;135(2):261-71. doi: 10.1016/j.cell.2008.08.016. Cell. 2008. PMID: 18957201 Free PMC article.
288 results