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Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension.
Zawia A, Arnold ND, West L, Pickworth JA, Turton H, Iremonger J, Braithwaite AT, Cañedo J, Johnston SA, Thompson AAR, Miller G, Lawrie A. Zawia A, et al. Among authors: west l. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):430-445. doi: 10.1161/ATVBAHA.120.314639. Epub 2020 Nov 5. Arterioscler Thromb Vasc Biol. 2021. PMID: 33147993 Free PMC article.
Platelet P2Y12 Inhibitors Reduce Systemic Inflammation and Its Prothrombotic Effects in an Experimental Human Model.
Thomas MR, Outteridge SN, Ajjan RA, Phoenix F, Sangha GK, Faulkner RE, Ecob R, Judge HM, Khan H, West LE, Dockrell DH, Sabroe I, Storey RF. Thomas MR, et al. Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2562-70. doi: 10.1161/ATVBAHA.115.306528. Epub 2015 Oct 29. Arterioscler Thromb Vasc Biol. 2015. PMID: 26515417 Free PMC article. Clinical Trial.
Selective improvement of pulmonary arterial hypertension with a dual ETA/ETB receptors antagonist in the apolipoprotein E-/- model of PAH and atherosclerosis.
Renshall L, Arnold N, West L, Braithwaite A, Pickworth J, Walker R, Alfaidi M, Chamberlain J, Casbolt H, Thompson AAR, Holt C, Iglarz M, Francis S, Lawrie A. Renshall L, et al. Among authors: west l. Pulm Circ. 2018 Jan-Mar;8(1):2045893217752328. doi: 10.1177/2045893217752328. Epub 2017 Dec 20. Pulm Circ. 2018. PMID: 29261014 Free PMC article.
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension.
Arnold ND, Pickworth JA, West LE, Dawson S, Carvalho JA, Casbolt H, Braithwaite AT, Iremonger J, Renshall L, Germaschewski V, McCourt M, Bland-Ward P, Kowash H, Hameed AG, Rothman AMK, Frid MG, Roger Thompson AA, Evans HR, Southwood M, Morrell NW, Crossman DC, Whyte MKB, Stenmark KR, Newman CM, Kiely DG, Francis SE, Lawrie A. Arnold ND, et al. Among authors: west le. Nat Commun. 2019 Nov 15;10(1):5183. doi: 10.1038/s41467-019-13139-9. Nat Commun. 2019. PMID: 31729368 Free PMC article.
Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium.
Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L, Long M, Parry S, Woods R, Hulston C, Benedikter B, Niespolo C, Bazaz R, Francis S, Kiss-Toth E, van Zandvoort M, Schober A, Hellewell P, Evans PC, Ridger V. Gomez I, et al. Among authors: west l. Nat Commun. 2020 Jan 10;11(1):214. doi: 10.1038/s41467-019-14043-y. Nat Commun. 2020. PMID: 31924781 Free PMC article.
Mast cells in pathological and surgical scars.
Beer TW, Baldwin H, West L, Gallagher PJ, Wright DH. Beer TW, et al. Among authors: west l. Br J Ophthalmol. 1998 Jun;82(6):691-4. doi: 10.1136/bjo.82.6.691. Br J Ophthalmol. 1998. PMID: 9797674 Free PMC article.
681 results