West GM - Search Results

1

Thermodynamic analysis of protein-ligand binding interactions in complex biological mixtures using the stability of proteins from rates of oxidation.

Strickland EC, Geer MA, Tran DT, Adhikari J, West GM, DeArmond PD, Xu Y, Fitzgerald MC. Strickland EC, et al. Among authors: west gm. Nat Protoc. 2013 Jan;8(1):148-61. doi: 10.1038/nprot.2012.146. Epub 2012 Dec 20. Nat Protoc. 2013. PMID: 23257983 Free PMC article.

2

Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy.

West GM, Tang L, Fitzgerald MC. West GM, et al. Anal Chem. 2008 Jun 1;80(11):4175-85. doi: 10.1021/ac702610a. Epub 2008 May 6. Anal Chem. 2008. PMID: 18457414

3

Painting proteins with covalent labels: what's in the picture?

Fitzgerald MC, West GM. Fitzgerald MC, et al. Among authors: west gm. J Am Soc Mass Spectrom. 2009 Jun;20(6):1193-206. doi: 10.1016/j.jasms.2009.02.006. Epub 2009 Feb 12. J Am Soc Mass Spectrom. 2009. PMID: 19269190 Free article.

4

Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.

West GM, Tucker CL, Xu T, Park SK, Han X, Yates JR 3rd, Fitzgerald MC. West GM, et al. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9078-82. doi: 10.1073/pnas.1000148107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439767 Free PMC article.

5

Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.

West GM, Thompson JW, Soderblom EJ, Dubois LG, Dearmond PD, Moseley MA, Fitzgerald MC. West GM, et al. Anal Chem. 2010 Jul 1;82(13):5573-81. doi: 10.1021/ac100465a. Anal Chem. 2010. PMID: 20527820

6

Discovery of novel cyclophilin A ligands using an H/D exchange- and mass spectrometry-based strategy.

Dearmond PD, West GM, Anbalagan V, Campa MJ, Patz EF Jr, Fitzgerald MC. Dearmond PD, et al. Among authors: west gm. J Biomol Screen. 2010 Oct;15(9):1051-62. doi: 10.1177/1087057110382775. Epub 2010 Sep 20. J Biomol Screen. 2010. PMID: 20855564 Free PMC article.

7

Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures.

DeArmond PD, West GM, Huang HT, Fitzgerald MC. DeArmond PD, et al. Among authors: west gm. J Am Soc Mass Spectrom. 2011 Mar;22(3):418-30. doi: 10.1007/s13361-010-0060-1. Epub 2011 Feb 1. J Am Soc Mass Spectrom. 2011. PMID: 21472561 Free PMC article.

8

Global analysis of protein folding thermodynamics for disease state characterization.

Adhikari J, West GM, Fitzgerald MC. Adhikari J, et al. Among authors: west gm. J Proteome Res. 2015 May 1;14(5):2287-97. doi: 10.1021/acs.jproteome.5b00057. Epub 2015 Apr 9. J Proteome Res. 2015. PMID: 25825992 Free PMC article.

9

Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors.

Zuhl AM, Nolan CE, Brodney MA, Niessen S, Atchison K, Houle C, Karanian DA, Ambroise C, Brulet JW, Beck EM, Doran SD, O'Neill BT, Am Ende CW, Chang C, Geoghegan KF, West GM, Judkins JC, Hou X, Riddell DR, Johnson DS. Zuhl AM, et al. Among authors: west gm. Nat Commun. 2016 Oct 11;7:13042. doi: 10.1038/ncomms13042. Nat Commun. 2016. PMID: 27727204 Free PMC article.

10

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions.

Chalmers MJ, Busby SA, Pascal BD, West GM, Griffin PR. Chalmers MJ, et al. Among authors: west gm. Expert Rev Proteomics. 2011 Feb;8(1):43-59. doi: 10.1586/epr.10.109. Expert Rev Proteomics. 2011. PMID: 21329427 Free PMC article. Review.

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