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Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Chauss D, et al. Among authors: west ee. Nat Immunol. 2022 Jan;23(1):62-74. doi: 10.1038/s41590-021-01080-3. Epub 2021 Nov 11. Nat Immunol. 2022. PMID: 34764490 Free PMC article.
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.
Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C. Arbore G, et al. Among authors: west ee. Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210. Science. 2016. PMID: 27313051 Free PMC article.
Complement and the Regulation of T Cell Responses.
West EE, Kolev M, Kemper C. West EE, et al. Annu Rev Immunol. 2018 Apr 26;36:309-338. doi: 10.1146/annurev-immunol-042617-053245. Annu Rev Immunol. 2018. PMID: 29677470 Free PMC article. Review.
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.
Arbore G, West EE, Rahman J, Le Friec G, Niyonzima N, Pirooznia M, Tunc I, Pavlidis P, Powell N, Li Y, Liu P, Servais A, Couzi L, Fremeaux-Bacchi V, Placais L, Ferraro A, Walsh PR, Kavanagh D, Afzali B, Lavender P, Lachmann HJ, Kemper C. Arbore G, et al. Among authors: west ee. Nat Commun. 2018 Oct 10;9(1):4186. doi: 10.1038/s41467-018-06706-z. Nat Commun. 2018. PMID: 30305631 Free PMC article.
Complement and T Cell Metabolism: Food for Thought.
West EE, Kemper C. West EE, et al. Immunometabolism. 2019 Jun 20;1(T Cell Metabolic Reprogramming):e190006. doi: 10.20900/immunometab20190006. Immunometabolism. 2019. PMID: 31328019 Free PMC article.
62 results