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Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types.
Naderi E, Aguado-Barrera ME, Schack LMH, Dorling L, Rattay T, Fachal L, Summersgill H, Martínez-Calvo L, Welsh C, Dudding T, Odding Y, Varela-Pazos A, Jena R, Thomson DJ, Steenbakkers RJHM, Dennis J, Lobato-Busto R, Alsner J, Ness A, Nutting C, Gómez-Caamaño A, Eriksen JG, Thomas SJ, Bates AM, Webb AJ, Choudhury A, Rosenstein BS, Taboada-Valladares B, Herskind C, Azria D, Dearnaley DP, de Ruysscher D, Sperk E, Hall E, Stobart H, Chang-Claude J, De Ruyck K, Veldeman L, Altabas M, De Santis MC, Farcy-Jacquet MP, Veldwijk MR, Sydes MR, Parliament M, Usmani N, Burnet NG, Seibold P, Symonds RP, Elliott RM, Bultijnck R, Gutiérrez-Enríquez S, Mollà M, Gulliford SL, Green S, Rancati T, Reyes V, Carballo A, Peleteiro P, Sosa-Fajardo P, Parker C, Fonteyne V, Johnson K, Lambrecht M, Vanneste B, Valdagni R, Giraldo A, Ramos M, Diergaarde B, Liu G, Leal SM, Chua MLK, Pring M, Overgaard J, Cascallar-Caneda LM, Duprez F, Talbot CJ, Barnett GC, Dunning AM, Vega A, Andreassen CN, Langendijk JA, West CML, Alizadeh BZ, Kerns SL; Radiogenomics Consortium. Naderi E, et al. Among authors: west cml. JNCI Cancer Spectr. 2023 Oct 31;7(6):pkad088. doi: 10.1093/jncics/pkad088. JNCI Cancer Spectr. 2023. PMID: 37862240 Free PMC article.
Radiosensitivity, radiogenomics and RAPPER.
Burnet NG, Elliott RM, Dunning A, West CM. Burnet NG, et al. Clin Oncol (R Coll Radiol). 2006 Sep;18(7):525-8. doi: 10.1016/j.clon.2006.05.007. Clin Oncol (R Coll Radiol). 2006. PMID: 16969982 No abstract available.
The genomics revolution and radiotherapy.
West CM, Elliott RM, Burnet NG. West CM, et al. Clin Oncol (R Coll Radiol). 2007 Aug;19(6):470-80. doi: 10.1016/j.clon.2007.02.016. Epub 2007 Apr 6. Clin Oncol (R Coll Radiol). 2007. PMID: 17419040 Review.
Standardized Total Average Toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies.
Barnett GC, West CM, Coles CE, Pharoah PD, Talbot CJ, Elliott RM, Tanteles GA, Symonds RP, Wilkinson JS, Dunning AM, Burnet NG, Bentzen SM. Barnett GC, et al. Int J Radiat Oncol Biol Phys. 2012 Mar 1;82(3):1065-74. doi: 10.1016/j.ijrobp.2011.03.015. Epub 2011 May 24. Int J Radiat Oncol Biol Phys. 2012. PMID: 21605943
Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study.
Barnett GC, Coles CE, Elliott RM, Baynes C, Luccarini C, Conroy D, Wilkinson JS, Tyrer J, Misra V, Platte R, Gulliford SL, Sydes MR, Hall E, Bentzen SM, Dearnaley DP, Burnet NG, Pharoah PD, Dunning AM, West CM. Barnett GC, et al. Lancet Oncol. 2012 Jan;13(1):65-77. doi: 10.1016/S1470-2045(11)70302-3. Epub 2011 Dec 12. Lancet Oncol. 2012. PMID: 22169268 Free article. Clinical Trial.
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