Induction of ALP and MMP9 activity facilitates invasive behavior in heterogeneous human BMSC and HNSCC 3D spheroids.
Wessely A, Waltera A, Reichert TE, Stöckl S, Grässel S, Bauer RJ.
Wessely A, et al.
FASEB J. 2019 Nov;33(11):11884-11893. doi: 10.1096/fj.201900925R. Epub 2019 Jul 31.
FASEB J. 2019.
PMID: 31366234
Free PMC article.
In head and neck squamous cell carcinoma (HNSCC), BMSCs are reported to be enriched with a potential negative role. Here, we evaluated the effect of BMSCs from 4 different donors in combination with 4 HNSCC cell lines in a 3-dimensional multicellular spheroid model. …
In head and neck squamous cell carcinoma (HNSCC), BMSCs are reported to be enriched with a potential negative role. Here, we evaluate …