Wessels LFA - Search Results

1

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer.

Annunziato S, de Ruiter JR, Henneman L, Brambillasca CS, Lutz C, Vaillant F, Ferrante F, Drenth AP, van der Burg E, Siteur B, van Gerwen B, de Bruijn R, van Miltenburg MH, Huijbers IJ, van de Ven M, Visvader JE, Lindeman GJ, Wessels LFA, Jonkers J. Annunziato S, et al. Among authors: wessels lfa. Nat Commun. 2019 Jan 23;10(1):397. doi: 10.1038/s41467-019-08301-2. Nat Commun. 2019. PMID: 30674894 Free PMC article.

2

MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer.

Theodorou V, Kimm MA, Boer M, Wessels L, Theelen W, Jonkers J, Hilkens J. Theodorou V, et al. Nat Genet. 2007 Jun;39(6):759-69. doi: 10.1038/ng2034. Epub 2007 Apr 29. Nat Genet. 2007. PMID: 17468756

3

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

Liu X, Holstege H, van der Gulden H, Treur-Mulder M, Zevenhoven J, Velds A, Kerkhoven RM, van Vliet MH, Wessels LF, Peterse JL, Berns A, Jonkers J. Liu X, et al. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12111-6. doi: 10.1073/pnas.0702969104. Epub 2007 Jul 11. Proc Natl Acad Sci U S A. 2007. PMID: 17626182 Free PMC article.

4

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data.

Klijn C, Holstege H, de Ridder J, Liu X, Reinders M, Jonkers J, Wessels L. Klijn C, et al. Nucleic Acids Res. 2008 Feb;36(2):e13. doi: 10.1093/nar/gkm1143. Epub 2008 Jan 10. Nucleic Acids Res. 2008. PMID: 18187509 Free PMC article.

5

Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.

Uren AG, Kool J, Matentzoglu K, de Ridder J, Mattison J, van Uitert M, Lagcher W, Sie D, Tanger E, Cox T, Reinders M, Hubbard TJ, Rogers J, Jonkers J, Wessels L, Adams DJ, van Lohuizen M, Berns A. Uren AG, et al. Cell. 2008 May 16;133(4):727-41. doi: 10.1016/j.cell.2008.03.021. Cell. 2008. PMID: 18485879 Free PMC article.

6

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

Klijn C, Bot J, Adams DJ, Reinders M, Wessels L, Jonkers J. Klijn C, et al. PLoS Comput Biol. 2010 Jan;6(1):e1000631. doi: 10.1371/journal.pcbi.1000631. Epub 2010 Jan 1. PLoS Comput Biol. 2010. PMID: 20052266 Free PMC article.

7

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

Kool J, Uren AG, Martins CP, Sie D, de Ridder J, Turner G, van Uitert M, Matentzoglu K, Lagcher W, Krimpenfort P, Gadiot J, Pritchard C, Lenz J, Lund AH, Jonkers J, Rogers J, Adams DJ, Wessels L, Berns A, van Lohuizen M. Kool J, et al. Cancer Res. 2010 Jan 15;70(2):520-31. doi: 10.1158/0008-5472.CAN-09-2736. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068150 Free PMC article.

8

Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach.

Mattison J, Kool J, Uren AG, de Ridder J, Wessels L, Jonkers J, Bignell GR, Butler A, Rust AG, Brosch M, Wilson CH, van der Weyden L, Largaespada DA, Stratton MR, Futreal PA, van Lohuizen M, Berns A, Collier LS, Hubbard T, Adams DJ. Mattison J, et al. Cancer Res. 2010 Feb 1;70(3):883-95. doi: 10.1158/0008-5472.CAN-09-1737. Epub 2010 Jan 26. Cancer Res. 2010. PMID: 20103622 Free PMC article.

9

Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers.

Holstege H, van Beers E, Velds A, Liu X, Joosse SA, Klarenbeek S, Schut E, Kerkhoven R, Klijn CN, Wessels LF, Nederlof PM, Jonkers J. Holstege H, et al. BMC Cancer. 2010 Aug 24;10:455. doi: 10.1186/1471-2407-10-455. BMC Cancer. 2010. PMID: 20735817 Free PMC article.

10

Somatic structural rearrangements in genetically engineered mouse mammary tumors.

Varela I, Klijn C, Stephens PJ, Mudie LJ, Stebbings L, Galappaththige D, van der Gulden H, Schut E, Klarenbeek S, Campbell PJ, Wessels LF, Stratton MR, Jonkers J, Futreal PA, Adams DJ. Varela I, et al. Genome Biol. 2010;11(10):R100. doi: 10.1186/gb-2010-11-10-r100. Epub 2010 Oct 13. Genome Biol. 2010. PMID: 20942901 Free PMC article.

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