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CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors.
Duurland CL, Santegoets SJ, Abdulrahman Z, Loof NM, Sturm G, Wesselink TH, Arens R, Boekestijn S, Ehsan I, van Poelgeest MIE, Finotello F, Hackl H, Trajanoski Z, Ten Dijke P, Braud VM, Welters MJP, van der Burg SH. Duurland CL, et al. Among authors: wesselink th. J Immunother Cancer. 2022 Jan;10(1):e003995. doi: 10.1136/jitc-2021-003995. J Immunother Cancer. 2022. PMID: 35039463 Free PMC article.
T RM maintenance is regulated by tissue damage via P2RX7.
Stark R, Wesselink TH, Behr FM, Kragten NAM, Arens R, Koch-Nolte F, van Gisbergen KPJM, van Lier RAW. Stark R, et al. Among authors: wesselink th. Sci Immunol. 2018 Dec 14;3(30):eaau1022. doi: 10.1126/sciimmunol.aau1022. Sci Immunol. 2018. PMID: 30552101
Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells.
Kragten NAM, Behr FM, Vieira Braga FA, Remmerswaal EBM, Wesselink TH, Oja AE, Hombrink P, Kallies A, van Lier RAW, Stark R, van Gisbergen KPJM. Kragten NAM, et al. Among authors: wesselink th. Eur J Immunol. 2018 Oct;48(10):1644-1662. doi: 10.1002/eji.201847771. Epub 2018 Aug 16. Eur J Immunol. 2018. PMID: 30051906 Free article.
Murine iNKT cells are depleted by liver damage via activation of P2RX7.
Bovens AA, Wesselink TH, Behr FM, Kragten NAM, van Lier RAW, van Gisbergen KPJM, Stark R. Bovens AA, et al. Among authors: wesselink th. Eur J Immunol. 2020 Oct;50(10):1515-1524. doi: 10.1002/eji.201948509. Epub 2020 May 27. Eur J Immunol. 2020. PMID: 32390174 Free article.
Hobit identifies tissue-resident memory T cell precursors that are regulated by Eomes.
Parga-Vidal L, Behr FM, Kragten NAM, Nota B, Wesselink TH, Kavazović I, Covill LE, Schuller MBP, Bryceson YT, Wensveen FM, van Lier RAW, van Dam TJP, Stark R, van Gisbergen KPJM. Parga-Vidal L, et al. Among authors: wesselink th. Sci Immunol. 2021 Aug 20;6(62):eabg3533. doi: 10.1126/sciimmunol.abg3533. Sci Immunol. 2021. PMID: 34417257
OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum.
van der Sluis TC, Beyrend G, van der Gracht ETI, Abdelaal T, Jochems SP, Belderbos RA, Wesselink TH, van Duikeren S, van Haften FJ, Redeker A, Ouboter LF, Beyranvand Nejad E, Camps M, Franken KLMC, Linssen MM, Hohenstein P, de Miranda NFCC, Mei H, Bins AD, Haanen JBAG, Aerts JG, Ossendorp F, Arens R. van der Sluis TC, et al. Among authors: wesselink th. Cell Rep Med. 2023 Mar 21;4(3):100939. doi: 10.1016/j.xcrm.2023.100939. Epub 2023 Feb 15. Cell Rep Med. 2023. PMID: 36796366 Free PMC article.