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Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum.
Barber BE, Abd-Rahman AN, Webster R, Potter AJ, Llewellyn S, Marquart L, Sahai N, Leelasena I, Birrell GW, Edstein MD, Shanks GD, Wesche D, Moehrle JJ, McCarthy JS. Barber BE, et al. Among authors: wesche d. Clin Infect Dis. 2023 Jun 8;76(11):1919-1927. doi: 10.1093/cid/ciad075. Clin Infect Dis. 2023. PMID: 36795050 Free PMC article.
Development and application of a PBPK modeling strategy to support antimalarial drug development.
Abla N, Howgate E, Rowland-Yeo K, Dickins M, Bergagnini-Kolev MC, Chen KF, McFeely S, Bonner JJ, Santos LGA, Gobeau N, Burt H, Barter Z, Jones HM, Wesche D, Charman SA, Möhrle JJ, Burrows JN, Almond LM. Abla N, et al. Among authors: wesche d. CPT Pharmacometrics Syst Pharmacol. 2023 Sep;12(9):1335-1346. doi: 10.1002/psp4.13013. Epub 2023 Aug 16. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37587640 Free PMC article.
Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure.
Pottenger AE, Roy D, Srinivasan S, Chavas TEJ, Vlaskin V, Ho DK, Livingston VC, Maktabi M, Lin H, Zhang J, Pybus B, Kudyba K, Roth A, Senter P, Tyson G, Huber HE, Wesche D, Rochford R, Burke PA, Stayton PS. Pottenger AE, et al. Among authors: wesche d. Sci Adv. 2024 Apr 19;10(16):eadk4492. doi: 10.1126/sciadv.adk4492. Epub 2024 Apr 19. Sci Adv. 2024. PMID: 38640243 Free PMC article.
Correction to: R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini.
Falcoz C, Guzy S, Kovač J, Meister I, Coulibaly J, Sayasone S, Wesche D, Lin YW, Keiser J. Falcoz C, et al. Among authors: wesche d. J Pharmacokinet Pharmacodyn. 2022 Jun;49(3):395. doi: 10.1007/s10928-022-09807-x. J Pharmacokinet Pharmacodyn. 2022. PMID: 35119619 No abstract available.
R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini.
Falcoz C, Guzy S, Kovač J, Meister I, Coulibaly J, Sayasone S, Wesche D, Lin YW, Keiser J. Falcoz C, et al. Among authors: wesche d. J Pharmacokinet Pharmacodyn. 2022 Jun;49(3):293-310. doi: 10.1007/s10928-021-09791-8. Epub 2022 Jan 13. J Pharmacokinet Pharmacodyn. 2022. PMID: 35024995
Model-Informed Drug Development for Anti-Infectives: State of the Art and Future.
Rayner CR, Smith PF, Andes D, Andrews K, Derendorf H, Friberg LE, Hanna D, Lepak A, Mills E, Polasek TM, Roberts JA, Schuck V, Shelton MJ, Wesche D, Rowland-Yeo K. Rayner CR, et al. Among authors: wesche d. Clin Pharmacol Ther. 2021 Apr;109(4):867-891. doi: 10.1002/cpt.2198. Epub 2021 Mar 9. Clin Pharmacol Ther. 2021. PMID: 33555032 Free PMC article. Review.
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