Wertz M - Search Results

1

Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin.

Megret L, Gris B, Sasidharan Nair S, Cevost J, Wertz M, Aaronson J, Rosinski J, Vogt TF, Wilkinson H, Heiman M, Neri C. Megret L, et al. Among authors: wertz m. Elife. 2021 Feb 23;10:e64984. doi: 10.7554/eLife.64984. Elife. 2021. PMID: 33618800 Free PMC article.

2

Interleukin-6 deficiency exacerbates Huntington's disease model phenotypes.

Wertz MH, Pineda SS, Lee H, Kulicke R, Kellis M, Heiman M. Wertz MH, et al. Mol Neurodegener. 2020 May 24;15(1):29. doi: 10.1186/s13024-020-00379-3. Mol Neurodegener. 2020. PMID: 32448329 Free PMC article.

3

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.

Wertz MH, Mitchem MR, Pineda SS, Hachigian LJ, Lee H, Lau V, Powers A, Kulicke R, Madan GK, Colic M, Therrien M, Vernon A, Beja-Glasser VF, Hegde M, Gao F, Kellis M, Hart T, Doench JG, Heiman M. Wertz MH, et al. Neuron. 2020 Apr 8;106(1):76-89.e8. doi: 10.1016/j.neuron.2020.01.004. Epub 2020 Jan 30. Neuron. 2020. PMID: 32004439 Free PMC article.

4

Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis.

Kong SW, Sahin M, Collins CD, Wertz MH, Campbell MG, Leech JD, Krueger D, Bear MF, Kunkel LM, Kohane IS. Kong SW, et al. Among authors: wertz mh. Mol Autism. 2014 Feb 24;5(1):16. doi: 10.1186/2040-2392-5-16. Mol Autism. 2014. PMID: 24564913 Free PMC article.

5

Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy.

Wertz MH, Winden K, Neveu P, Ng SY, Ercan E, Sahin M. Wertz MH, et al. Hum Mol Genet. 2016 Jun 1;25(11):2168-2181. doi: 10.1093/hmg/ddw084. Epub 2016 Mar 22. Hum Mol Genet. 2016. PMID: 27005422 Free PMC article.

6

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.

Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M. Di Nardo A, et al. Among authors: wertz mh. Hum Mol Genet. 2014 Jul 15;23(14):3865-74. doi: 10.1093/hmg/ddu101. Epub 2014 Mar 5. Hum Mol Genet. 2014. PMID: 24599401 Free PMC article.

7

Developing therapies for spinal muscular atrophy.

Wertz MH, Sahin M. Wertz MH, et al. Ann N Y Acad Sci. 2016 Feb;1366(1):5-19. doi: 10.1111/nyas.12813. Epub 2015 Jul 14. Ann N Y Acad Sci. 2016. PMID: 26173388 Free PMC article. Review.

8

SMN regulates axonal local translation via miR-183/mTOR pathway.

Kye MJ, Niederst ED, Wertz MH, Gonçalves Ido C, Akten B, Dover KZ, Peters M, Riessland M, Neveu P, Wirth B, Kosik KS, Sardi SP, Monani UR, Passini MA, Sahin M. Kye MJ, et al. Among authors: wertz mh. Hum Mol Genet. 2014 Dec 1;23(23):6318-31. doi: 10.1093/hmg/ddu350. Epub 2014 Jul 4. Hum Mol Genet. 2014. PMID: 25055867 Free PMC article.

9

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.

Akten B, Kye MJ, Hao le T, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen JA, Sahin M. Akten B, et al. Among authors: wertz mh. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10337-42. doi: 10.1073/pnas.1104928108. Epub 2011 Jun 7. Proc Natl Acad Sci U S A. 2011. PMID: 21652774 Free PMC article.

10

BACE1 regulates voltage-gated sodium channels and neuronal activity.

Kim DY, Carey BW, Wang H, Ingano LA, Binshtok AM, Wertz MH, Pettingell WH, He P, Lee VM, Woolf CJ, Kovacs DM. Kim DY, et al. Among authors: wertz mh. Nat Cell Biol. 2007 Jul;9(7):755-64. doi: 10.1038/ncb1602. Epub 2007 Jun 18. Nat Cell Biol. 2007. PMID: 17576410 Free PMC article.

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