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Synthesis and reactivity of precolibactin 886.
Healy AR, Wernke KM, Kim CS, Lees NR, Crawford JM, Herzon SB. Healy AR, et al. Among authors: wernke km. Nat Chem. 2019 Oct;11(10):890-898. doi: 10.1038/s41557-019-0338-2. Epub 2019 Sep 23. Nat Chem. 2019. PMID: 31548676 Free PMC article.
Structure elucidation of colibactin and its DNA cross-links.
Xue M, Kim CS, Healy AR, Wernke KM, Wang Z, Frischling MC, Shine EE, Wang W, Herzon SB, Crawford JM. Xue M, et al. Among authors: wernke km. Science. 2019 Sep 6;365(6457):eaax2685. doi: 10.1126/science.aax2685. Epub 2019 Aug 8. Science. 2019. PMID: 31395743 Free PMC article.
Addendum: Synthesis and reactivity of precolibactin 886.
Healy AR, Wernke KM, Kim CS, Lees NR, Crawford JM, Herzon SB. Healy AR, et al. Among authors: wernke km. Nat Chem. 2019 Dec;11(12):1167. doi: 10.1038/s41557-019-0383-x. Nat Chem. 2019. PMID: 31719668 Free PMC article.
Depurination of Colibactin-Derived Interstrand Cross-Links.
Xue M, Wernke KM, Herzon SB. Xue M, et al. Among authors: wernke km. Biochemistry. 2020 Feb 25;59(7):892-900. doi: 10.1021/acs.biochem.9b01070. Epub 2020 Feb 13. Biochemistry. 2020. PMID: 31977191 Free PMC article.
Structure and bioactivity of colibactin.
Wernke KM, Xue M, Tirla A, Kim CS, Crawford JM, Herzon SB. Wernke KM, et al. Bioorg Med Chem Lett. 2020 Aug 1;30(15):127280. doi: 10.1016/j.bmcl.2020.127280. Epub 2020 May 23. Bioorg Med Chem Lett. 2020. PMID: 32527463 Free PMC article. Review.
The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links.
Altshuller M, He X, MacKrell EJ, Wernke KM, Wong JWH, Sellés-Baiget S, Wang TY, Chou TF, Duxin JP, Balskus EP, Herzon SB, Semlow DR. Altshuller M, et al. Among authors: wernke km. bioRxiv [Preprint]. 2024 Jan 31:2024.01.30.576698. doi: 10.1101/2024.01.30.576698. bioRxiv. 2024. PMID: 38352618 Free PMC article. Preprint.
11 results