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Oligodendrocytes support axonal transport and maintenance via exosome secretion.
Frühbeis C, Kuo-Elsner WP, Müller C, Barth K, Peris L, Tenzer S, Möbius W, Werner HB, Nave KA, Fröhlich D, Krämer-Albers EM. Frühbeis C, et al. Among authors: werner hb. PLoS Biol. 2020 Dec 22;18(12):e3000621. doi: 10.1371/journal.pbio.3000621. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33351792 Free PMC article.
Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5.
Buscham TJ, Eichel-Vogel MA, Steyer AM, Jahn O, Strenzke N, Dardawal R, Memhave TR, Siems SB, Müller C, Meschkat M, Sun T, Ruhwedel T, Möbius W, Krämer-Albers EM, Boretius S, Nave KA, Werner HB. Buscham TJ, et al. Among authors: werner hb. Elife. 2022 Mar 11;11:e75523. doi: 10.7554/eLife.75523. Elife. 2022. PMID: 35274615 Free PMC article.
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.
Depp C, Sun T, Sasmita AO, Spieth L, Berghoff SA, Nazarenko T, Overhoff K, Steixner-Kumar AA, Subramanian S, Arinrad S, Ruhwedel T, Möbius W, Göbbels S, Saher G, Werner HB, Damkou A, Zampar S, Wirths O, Thalmann M, Simons M, Saito T, Saido T, Krueger-Burg D, Kawaguchi R, Willem M, Haass C, Geschwind D, Ehrenreich H, Stassart R, Nave KA. Depp C, et al. Among authors: werner hb. Nature. 2023 Jun;618(7964):349-357. doi: 10.1038/s41586-023-06120-6. Epub 2023 May 31. Nature. 2023. PMID: 37258678 Free PMC article.
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, Möbius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA. Werner HB, et al. J Neurosci. 2007 Jul 18;27(29):7717-30. doi: 10.1523/JNEUROSCI.1254-07.2007. J Neurosci. 2007. PMID: 17634366 Free PMC article.
73 results