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T-cells of invasive candidiasis patients show patterns of T-cell-exhaustion suggesting checkpoint blockade as treatment option.
Mellinghoff SC, Thelen M, Bruns C, Garcia-Marquez M, Hartmann P, Lammertz T, Lehmann J, Nowag A, Stemler J, Wennhold K, Cornely OA, von Bergwelt-Baildon MS, Schlößer HA. Mellinghoff SC, et al. Among authors: wennhold k. J Infect. 2022 Feb;84(2):237-247. doi: 10.1016/j.jinf.2021.12.009. Epub 2021 Dec 15. J Infect. 2022. PMID: 34921845 Clinical Trial.
Using Antigen-Specific B Cells to Combine Antibody and T Cell-Based Cancer Immunotherapy.
Wennhold K, Thelen M, Schlößer HA, Haustein N, Reuter S, Garcia-Marquez M, Lechner A, Kobold S, Rataj F, Utermöhlen O, Chakupurakal G, Theurich S, Hallek M, Abken H, Shimabukuro-Vornhagen A, von Bergwelt-Baildon M. Wennhold K, et al. Cancer Immunol Res. 2017 Sep;5(9):730-743. doi: 10.1158/2326-6066.CIR-16-0236. Epub 2017 Aug 4. Cancer Immunol Res. 2017. PMID: 28778961
Characterization of tumor-associated B-cell subsets in patients with colorectal cancer.
Shimabukuro-Vornhagen A, Schlößer HA, Gryschok L, Malcher J, Wennhold K, Garcia-Marquez M, Herbold T, Neuhaus LS, Becker HJ, Fiedler A, Scherwitz P, Koslowsky T, Hake R, Stippel DL, Hölscher AH, Eidt S, Hallek M, Theurich S, von Bergwelt-Baildon MS. Shimabukuro-Vornhagen A, et al. Among authors: wennhold k. Oncotarget. 2014 Jul 15;5(13):4651-64. doi: 10.18632/oncotarget.1701. Oncotarget. 2014. PMID: 25026291 Free PMC article.
B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies.
Schlößer HA, Thelen M, Lechner A, Wennhold K, Garcia-Marquez MA, Rothschild SI, Staib E, Zander T, Beutner D, Gathof B, Gilles R, Cukuroglu E, Göke J, Shimabukuro-Vornhagen A, Drebber U, Quaas A, Bruns CJ, Hölscher AH, Von Bergwelt-Baildon MS. Schlößer HA, et al. Among authors: wennhold k. Oncoimmunology. 2018 Nov 2;8(1):e1512458. doi: 10.1080/2162402X.2018.1512458. eCollection 2019. Oncoimmunology. 2018. PMID: 30546950 Free PMC article.
Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma.
Lechner A, Schlößer HA, Thelen M, Wennhold K, Rothschild SI, Gilles R, Quaas A, Siefer OG, Huebbers CU, Cukuroglu E, Göke J, Hillmer A, Gathof B, Meyer MF, Klussmann JP, Shimabukuro-Vornhagen A, Theurich S, Beutner D, von Bergwelt-Baildon M. Lechner A, et al. Among authors: wennhold k. Oncoimmunology. 2019 Jan 10;8(3):1535293. doi: 10.1080/2162402X.2018.1535293. eCollection 2019. Oncoimmunology. 2019. PMID: 30723574 Free PMC article.
CD86+ Antigen-Presenting B Cells Are Increased in Cancer, Localize in Tertiary Lymphoid Structures, and Induce Specific T-cell Responses.
Wennhold K, Thelen M, Lehmann J, Schran S, Preugszat E, Garcia-Marquez M, Lechner A, Shimabukuro-Vornhagen A, Ercanoglu MS, Klein F, Thangarajah F, Eidt S, Löser H, Bruns C, Quaas A, von Bergwelt-Baildon M, Schlößer HA. Wennhold K, et al. Cancer Immunol Res. 2021 Sep;9(9):1098-1108. doi: 10.1158/2326-6066.CIR-20-0949. Epub 2021 Jun 21. Cancer Immunol Res. 2021. PMID: 34155067
Post-transplant Malignancies Show Reduced T-cell Abundance and Tertiary Lymphoid Structures as Correlates of Impaired Cancer Immunosurveillance.
Datta RR, Schran S, Persa OD, Aguilar C, Thelen M, Lehmann J, Garcia-Marquez MA, Wennhold K, Preugszat E, Zentis P, von Bergwelt-Baildon MS, Quaas A, Bruns CJ, Kurschat C, Mauch C, Löser H, Stippel DL, Schlößer HA. Datta RR, et al. Among authors: wennhold k. Clin Cancer Res. 2022 Apr 14;28(8):1712-1723. doi: 10.1158/1078-0432.CCR-21-3746. Clin Cancer Res. 2022. PMID: 35191474
34 results