Wennerberg K - Search Results

1

Bioluminescent, Nonlytic, Real-Time Cell Viability Assay and Use in Inhibitor Screening.

Duellman SJ, Zhou W, Meisenheimer P, Vidugiris G, Cali JJ, Gautam P, Wennerberg K, Vidugiriene J. Duellman SJ, et al. Among authors: wennerberg k. Assay Drug Dev Technol. 2015 Oct;13(8):456-65. doi: 10.1089/adt.2015.669. Epub 2015 Sep 18. Assay Drug Dev Technol. 2015. PMID: 26383544 Free PMC article.

2

Bioluminescent cell-based NAD(P)/NAD(P)H assays for rapid dinucleotide measurement and inhibitor screening.

Vidugiriene J, Leippe D, Sobol M, Vidugiris G, Zhou W, Meisenheimer P, Gautam P, Wennerberg K, Cali JJ. Vidugiriene J, et al. Among authors: wennerberg k. Assay Drug Dev Technol. 2014 Nov-Dec;12(9-10):514-26. doi: 10.1089/adt.2014.605. Assay Drug Dev Technol. 2014. PMID: 25506801 Free PMC article.

3

Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth.

Al-Ali H, Lee DH, Danzi MC, Nassif H, Gautam P, Wennerberg K, Zuercher B, Drewry DH, Lee JK, Lemmon VP, Bixby JL. Al-Ali H, et al. Among authors: wennerberg k. ACS Chem Biol. 2015 Aug 21;10(8):1939-51. doi: 10.1021/acschembio.5b00289. Epub 2015 Jun 24. ACS Chem Biol. 2015. PMID: 26056718 Free PMC article.

4

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles.

Szwajda A, Gautam P, Karhinen L, Jha SK, Saarela J, Shakyawar S, Turunen L, Yadav B, Tang J, Wennerberg K, Aittokallio T. Szwajda A, et al. Among authors: wennerberg k. Chem Biol. 2015 Aug 20;22(8):1144-55. doi: 10.1016/j.chembiol.2015.06.021. Epub 2015 Jul 23. Chem Biol. 2015. PMID: 26211361

5

Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells.

Gautam P, Karhinen L, Szwajda A, Jha SK, Yadav B, Aittokallio T, Wennerberg K. Gautam P, et al. Among authors: wennerberg k. Mol Cancer. 2016 May 10;15(1):34. doi: 10.1186/s12943-016-0517-3. Mol Cancer. 2016. PMID: 27165605 Free PMC article.

6

Consistency in drug response profiling.

Mpindi JP, Yadav B, Östling P, Gautam P, Malani D, Murumägi A, Hirasawa A, Kangaspeska S, Wennerberg K, Kallioniemi O, Aittokallio T. Mpindi JP, et al. Among authors: wennerberg k. Nature. 2016 Nov 30;540(7631):E5-E6. doi: 10.1038/nature20171. Nature. 2016. PMID: 27905421 No abstract available.

7

Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets.

Gautam P, Jaiswal A, Aittokallio T, Al-Ali H, Wennerberg K. Gautam P, et al. Among authors: wennerberg k. Cell Chem Biol. 2019 Jul 18;26(7):970-979.e4. doi: 10.1016/j.chembiol.2019.03.011. Epub 2019 May 2. Cell Chem Biol. 2019. PMID: 31056464 Free PMC article.

8

Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer.

Tang J, Gautam P, Gupta A, He L, Timonen S, Akimov Y, Wang W, Szwajda A, Jaiswal A, Turei D, Yadav B, Kankainen M, Saarela J, Saez-Rodriguez J, Wennerberg K, Aittokallio T. Tang J, et al. Among authors: wennerberg k. NPJ Syst Biol Appl. 2019 Jul 8;5:20. doi: 10.1038/s41540-019-0098-z. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 31312514 Free PMC article.

9

A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening.

Gupta A, Gautam P, Wennerberg K, Aittokallio T. Gupta A, et al. Among authors: wennerberg k. Commun Biol. 2020 Jan 23;3(1):42. doi: 10.1038/s42003-020-0765-z. Commun Biol. 2020. PMID: 31974521 Free PMC article.

10

Prediction of drug combination effects with a minimal set of experiments.

Ianevski A, Giri AK, Gautam P, Kononov A, Potdar S, Saarela J, Wennerberg K, Aittokallio T. Ianevski A, et al. Among authors: wennerberg k. Nat Mach Intell. 2019 Dec;1(12):568-577. doi: 10.1038/s42256-019-0122-4. Epub 2019 Dec 9. Nat Mach Intell. 2019. PMID: 32368721 Free PMC article.

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