Wengel J - Search Results

1

Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs.

Gissberg O, Zaghloul EM, Lundin KE, Nguyen CH, Landras-Guetta C, Wengel J, Zain R, Smith CI. Gissberg O, et al. Among authors: wengel j. Nucleic Acid Ther. 2016 Jun;26(3):183-9. doi: 10.1089/nat.2015.0592. Epub 2016 Feb 9. Nucleic Acid Ther. 2016. PMID: 26859550

2

Locked nucleic acid as a novel class of therapeutic agents.

Veedu RN, Wengel J. Veedu RN, et al. Among authors: wengel j. RNA Biol. 2009 Jul-Aug;6(3):321-3. doi: 10.4161/rna.6.3.8807. Epub 2009 Jul 18. RNA Biol. 2009. PMID: 19458498 Free article. Review.

3

Thermodynamics of RNA duplexes modified with unlocked nucleic acid nucleotides.

Pasternak A, Wengel J. Pasternak A, et al. Among authors: wengel j. Nucleic Acids Res. 2010 Oct;38(19):6697-706. doi: 10.1093/nar/gkq561. Epub 2010 Jun 18. Nucleic Acids Res. 2010. PMID: 20562222 Free PMC article.

4

Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA.

Zaghloul EM, Madsen AS, Moreno PM, Oprea II, El-Andaloussi S, Bestas B, Gupta P, Pedersen EB, Lundin KE, Wengel J, Smith CI. Zaghloul EM, et al. Among authors: wengel j. Nucleic Acids Res. 2011 Feb;39(3):1142-54. doi: 10.1093/nar/gkq835. Epub 2010 Sep 21. Nucleic Acids Res. 2011. PMID: 20860997 Free PMC article.

5

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.

Pasternak A, Hernandez FJ, Rasmussen LM, Vester B, Wengel J. Pasternak A, et al. Among authors: wengel j. Nucleic Acids Res. 2011 Feb;39(3):1155-64. doi: 10.1093/nar/gkq823. Epub 2010 Sep 24. Nucleic Acids Res. 2011. PMID: 20870750 Free PMC article.

6

Unlocked nucleic acid--an RNA modification with broad potential.

Pasternak A, Wengel J. Pasternak A, et al. Among authors: wengel j. Org Biomol Chem. 2011 May 21;9(10):3591-7. doi: 10.1039/c0ob01085e. Epub 2011 Mar 23. Org Biomol Chem. 2011. PMID: 21431171 Review.

7

Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2'-C-piperazino-UNA monomer.

Jensen TB, Henriksen JR, Rasmussen BE, Rasmussen LM, Andresen TL, Wengel J, Pasternak A. Jensen TB, et al. Among authors: wengel j. Bioorg Med Chem. 2011 Aug 15;19(16):4739-45. doi: 10.1016/j.bmc.2011.06.087. Epub 2011 Jul 7. Bioorg Med Chem. 2011. PMID: 21795054

8

Locked nucleic acid and aptamers.

Karlsen KK, Wengel J. Karlsen KK, et al. Among authors: wengel j. Nucleic Acid Ther. 2012 Dec;22(6):366-70. doi: 10.1089/nat.2012.0382. Nucleic Acid Ther. 2012. PMID: 23181700 Free PMC article. No abstract available.

9

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.

Moreno PM, Geny S, Pabon YV, Bergquist H, Zaghloul EM, Rocha CS, Oprea II, Bestas B, Andaloussi SE, Jørgensen PT, Pedersen EB, Lundin KE, Zain R, Wengel J, Smith CI. Moreno PM, et al. Among authors: wengel j. Nucleic Acids Res. 2013 Mar 1;41(5):3257-73. doi: 10.1093/nar/gkt007. Epub 2013 Jan 23. Nucleic Acids Res. 2013. PMID: 23345620 Free PMC article.

10

Biological activity and biotechnological aspects of locked nucleic acids.

Lundin KE, Højland T, Hansen BR, Persson R, Bramsen JB, Kjems J, Koch T, Wengel J, Smith CI. Lundin KE, et al. Among authors: wengel j. Adv Genet. 2013;82:47-107. doi: 10.1016/B978-0-12-407676-1.00002-0. Adv Genet. 2013. PMID: 23721720 Review.

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