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Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, Gu LJ, Yan M, Zhang DE, Chen SJ, Wang ZY, Chen Z. Zhou GB, et al. Among authors: weng xq. Blood. 2007 Apr 15;109(8):3441-50. doi: 10.1182/blood-2006-06-032250. Epub 2006 Dec 29. Blood. 2007. PMID: 17197433 Free PMC article.
Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.
Liu YF, Wang BY, Zhang WN, Huang JY, Li BS, Zhang M, Jiang L, Li JF, Wang MJ, Dai YJ, Zhang ZG, Wang Q, Kong J, Chen B, Zhu YM, Weng XQ, Shen ZX, Li JM, Wang J, Yan XJ, Li Y, Liang YM, Liu L, Chen XQ, Zhang WG, Yan JS, Hu JD, Shen SH, Chen J, Gu LJ, Pei D, Li Y, Wu G, Zhou X, Ren RB, Cheng C, Yang JJ, Wang KK, Wang SY, Zhang J, Mi JQ, Pui CH, Tang JY, Chen Z, Chen SJ. Liu YF, et al. Among authors: weng xq. EBioMedicine. 2016 Jun;8:173-183. doi: 10.1016/j.ebiom.2016.04.038. Epub 2016 May 13. EBioMedicine. 2016. PMID: 27428428 Free PMC article.
Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia.
Chen B, Jiang L, Zhong ML, Li JF, Li BS, Peng LJ, Dai YT, Cui BW, Yan TQ, Zhang WN, Weng XQ, Xie YY, Lu J, Ren RB, Chen SN, Hu JD, Wu DP, Chen Z, Tang JY, Huang JY, Mi JQ, Chen SJ. Chen B, et al. Among authors: weng xq. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):373-378. doi: 10.1073/pnas.1717125115. Epub 2017 Dec 26. Proc Natl Acad Sci U S A. 2018. PMID: 29279377 Free PMC article.
Exploratory trial of a biepitopic CAR T-targeting B cell maturation antigen in relapsed/refractory multiple myeloma.
Xu J, Chen LJ, Yang SS, Sun Y, Wu W, Liu YF, Xu J, Zhuang Y, Zhang W, Weng XQ, Wu J, Wang Y, Wang J, Yan H, Xu WB, Jiang H, Du J, Ding XY, Li B, Li JM, Fu WJ, Zhu J, Zhu L, Chen Z, Fan XF, Hou J, Li JY, Mi JQ, Chen SJ. Xu J, et al. Among authors: weng xq. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9543-9551. doi: 10.1073/pnas.1819745116. Epub 2019 Apr 15. Proc Natl Acad Sci U S A. 2019. PMID: 30988175 Free PMC article. Clinical Trial.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation.
Wu SF, Xia L, Shi XD, Dai YJ, Zhang WN, Zhao JM, Zhang W, Weng XQ, Lu J, Le HY, Tao SC, Zhu J, Chen Z, Wang YY, Chen S. Wu SF, et al. Among authors: weng xq. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14395-14404. doi: 10.1073/pnas.1918596117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513696 Free PMC article.
52 results