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In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor.
Wen L, Tang K, Chik KK, Chan CC, Tsang JO, Liang R, Cao J, Huang Y, Luo C, Cai JP, Ye ZW, Yin F, Chu H, Jin DY, Yuen KY, Yuan S, Chan JF. Wen L, et al. Int J Biol Sci. 2021 Apr 10;17(6):1555-1564. doi: 10.7150/ijbs.59191. eCollection 2021. Int J Biol Sci. 2021. PMID: 33907519 Free PMC article.
Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus.
Zhou J, Li C, Zhao G, Chu H, Wang D, Yan HH, Poon VK, Wen L, Wong BH, Zhao X, Chiu MC, Yang D, Wang Y, Au-Yeung RKH, Chan IH, Sun S, Chan JF, To KK, Memish ZA, Corman VM, Drosten C, Hung IF, Zhou Y, Leung SY, Yuen KY. Zhou J, et al. Among authors: wen l. Sci Adv. 2017 Nov 15;3(11):eaao4966. doi: 10.1126/sciadv.aao4966. eCollection 2017 Nov. Sci Adv. 2017. PMID: 29152574 Free PMC article.
Inhibitors of Influenza A Virus Polymerase.
Yuan S, Wen L, Zhou J. Yuan S, et al. Among authors: wen l. ACS Infect Dis. 2018 Mar 9;4(3):218-223. doi: 10.1021/acsinfecdis.7b00265. Epub 2018 Jan 22. ACS Infect Dis. 2018. PMID: 29355011 Review.
Differentiated human airway organoids to assess infectivity of emerging influenza virus.
Zhou J, Li C, Sachs N, Chiu MC, Wong BH, Chu H, Poon VK, Wang D, Zhao X, Wen L, Song W, Yuan S, Wong KK, Chan JF, To KK, Chen H, Clevers H, Yuen KY. Zhou J, et al. Among authors: wen l. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6822-6827. doi: 10.1073/pnas.1806308115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891677 Free PMC article.
Establishment of a lethal aged mouse model of human respiratory syncytial virus infection.
Zhang K, Li C, Luo YS, Wen L, Yuan S, Wang D, Ho-Yin Wong B, Zhao X, Chiu MC, Ye ZW, Sun Z, Zhao H, Zhang X, Hu M, Yang D, Shuai H, Wang Y, He J, Bose ME, Henrickson KJ, Huang JD, Zheng B, Chu H, Zhou J. Zhang K, et al. Among authors: wen l. Antiviral Res. 2019 Jan;161:125-133. doi: 10.1016/j.antiviral.2018.11.015. Epub 2018 Nov 29. Antiviral Res. 2019. PMID: 30503888
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.
Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. Yuan S, et al. Among authors: wen l. Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x. Nat Commun. 2019. PMID: 30631056 Free PMC article.
4,692 results