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SUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling.
Zhao B, Gong W, Ma A, Chen J, Velegraki M, Dong H, Liu Z, Wang L, Okimoto T, Jones DM, Lei YL, Long M, Oestreich KJ, Ma Q, Xin G, Carbone DP, He K, Li Z, Wen H. Zhao B, et al. Among authors: wen h. Nat Immunol. 2022 Nov;23(11):1588-1599. doi: 10.1038/s41590-022-01326-8. Epub 2022 Oct 20. Nat Immunol. 2022. PMID: 36266363 Free PMC article.
O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Li X, Gong W, Wang H, Li T, Attri KS, Lewis RE, Kalil AC, Bhinderwala F, Powers R, Yin G, Herring LE, Asara JM, Lei YL, Yang X, Rodriguez DA, Yang M, Green DR, Singh PK, Wen H. Li X, et al. Among authors: wen h. Immunity. 2019 Mar 19;50(3):576-590.e6. doi: 10.1016/j.immuni.2019.01.007. Epub 2019 Feb 12. Immunity. 2019. PMID: 30770249 Free PMC article.
NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, Ting JP. Zhang L, et al. Among authors: wen h. Immunity. 2014 Mar 20;40(3):329-41. doi: 10.1016/j.immuni.2014.01.010. Epub 2014 Feb 20. Immunity. 2014. PMID: 24560620 Free PMC article.
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.
Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. Schneider M, et al. Among authors: wen h. Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5. Nat Immunol. 2012. PMID: 22863753 Free PMC article.
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.
Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL. Luo X, et al. Among authors: wen h. J Clin Invest. 2020 Apr 1;130(4):1635-1652. doi: 10.1172/JCI129497. J Clin Invest. 2020. PMID: 31874109 Free PMC article.
4,753 results