Welsh WJ - Search Results

1

Rational inhibitor design and iterative screening in the identification of selective plasmodial cyclin dependent kinase inhibitors.

Keenan SM, Geyer JA, Welsh WJ, Prigge ST, Waters NC. Keenan SM, et al. Among authors: welsh wj. Comb Chem High Throughput Screen. 2005 Feb;8(1):27-38. doi: 10.2174/1386207053328183. Comb Chem High Throughput Screen. 2005. PMID: 15720195 Review.

2

Characteristics of the Plasmodium falciparum PK5 ATP-binding site: implications for the design of novel antimalarial agents.

Keenan SM, Welsh WJ. Keenan SM, et al. Among authors: welsh wj. J Mol Graph Model. 2004 Jan;22(3):241-7. doi: 10.1016/j.jmgm.2003.09.002. J Mol Graph Model. 2004. PMID: 14629982

3

Structural model of the Plasmodium CDK, Pfmrk, a novel target for malaria therapeutics.

Peng Y, Keenan SM, Welsh WJ. Peng Y, et al. Among authors: welsh wj. J Mol Graph Model. 2005 Sep;24(1):72-80. doi: 10.1016/j.jmgm.2005.06.002. J Mol Graph Model. 2005. PMID: 16046158

4

3D-QSAR comparative molecular field analysis on opioid receptor antagonists: pooling data from different studies.

Peng Y, Keenan SM, Zhang Q, Kholodovych V, Welsh WJ. Peng Y, et al. Among authors: welsh wj. J Med Chem. 2005 Mar 10;48(5):1620-9. doi: 10.1021/jm049117e. J Med Chem. 2005. PMID: 15743203

5

Elucidation of the Na+, K+-ATPase digitalis binding site.

Keenan SM, DeLisle RK, Welsh WJ, Paula S, Ball WJ Jr. Keenan SM, et al. Among authors: welsh wj. J Mol Graph Model. 2005 Jun;23(6):465-75. doi: 10.1016/j.jmgm.2005.02.001. J Mol Graph Model. 2005. PMID: 15886034

6

3D-QSAR comparative molecular field analysis on delta opioid receptor agonist SNC80 and its analogs.

Peng Y, Keenan SM, Zhang Q, Welsh WJ. Peng Y, et al. Among authors: welsh wj. J Mol Graph Model. 2005 Sep;24(1):25-33. doi: 10.1016/j.jmgm.2005.05.001. J Mol Graph Model. 2005. PMID: 15950508

7

Discovery of novel triazole-based opioid receptor antagonists.

Zhang Q, Keenan SM, Peng Y, Nair AC, Yu SJ, Howells RD, Welsh WJ. Zhang Q, et al. Among authors: welsh wj. J Med Chem. 2006 Jul 13;49(14):4044-7. doi: 10.1021/jm0601250. J Med Chem. 2006. PMID: 16821764 Free PMC article.

8

Highly potent triazole-based tubulin polymerization inhibitors.

Zhang Q, Peng Y, Wang XI, Keenan SM, Arora S, Welsh WJ. Zhang Q, et al. Among authors: welsh wj. J Med Chem. 2007 Feb 22;50(4):749-54. doi: 10.1021/jm061142s. Epub 2007 Jan 24. J Med Chem. 2007. PMID: 17249649 Free PMC article.

9

Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk.

Woodard CL, Keenan SM, Gerena L, Welsh WJ, Geyer JA, Waters NC. Woodard CL, et al. Among authors: welsh wj. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4961-6. doi: 10.1016/j.bmcl.2007.06.032. Epub 2007 Jun 12. Bioorg Med Chem Lett. 2007. PMID: 17588749

10

Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.

Arora S, Wang XI, Keenan SM, Andaya C, Zhang Q, Peng Y, Welsh WJ. Arora S, et al. Among authors: welsh wj. Cancer Res. 2009 Mar 1;69(5):1910-5. doi: 10.1158/0008-5472.CAN-08-0877. Epub 2009 Feb 17. Cancer Res. 2009. PMID: 19223556 Free PMC article.

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