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Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in Mycobacterium abscessus.
Belardinelli JM, Verma D, Li W, Avanzi C, Wiersma CJ, Williams JT, Johnson BK, Zimmerman M, Whittel N, Angala B, Wang H, Jones V, Dartois V, de Moura VCN, Gonzalez-Juarrero M, Pearce C, Schenkel AR, Malcolm KC, Nick JA, Charman SA, Wells TNC, Podell BK, Vennerstrom JL, Ordway DJ, Abramovitch RB, Jackson M. Belardinelli JM, et al. Among authors: wells tnc. Sci Transl Med. 2022 Feb 23;14(633):eabj3860. doi: 10.1126/scitranslmed.abj3860. Epub 2022 Feb 23. Sci Transl Med. 2022. PMID: 35196022 Free PMC article.
Anticancer properties of distinct antimalarial drug classes.
Hooft van Huijsduijnen R, Guy RK, Chibale K, Haynes RK, Peitz I, Kelter G, Phillips MA, Vennerstrom JL, Yuthavong Y, Wells TN. Hooft van Huijsduijnen R, et al. PLoS One. 2013 Dec 31;8(12):e82962. doi: 10.1371/journal.pone.0082962. eCollection 2013. PLoS One. 2013. PMID: 24391728 Free PMC article.
The antimalarial pipeline.
Hooft van Huijsduijnen R, Wells TN. Hooft van Huijsduijnen R, et al. Curr Opin Pharmacol. 2018 Oct;42:1-6. doi: 10.1016/j.coph.2018.05.006. Epub 2018 May 31. Curr Opin Pharmacol. 2018. PMID: 29860174 Review.
Malaria medicines: a glass half full?
Wells TN, Hooft van Huijsduijnen R, Van Voorhis WC. Wells TN, et al. Nat Rev Drug Discov. 2015 Jun;14(6):424-42. doi: 10.1038/nrd4573. Epub 2015 May 22. Nat Rev Drug Discov. 2015. PMID: 26000721 Review.
Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.
Williamson AE, Ylioja PM, Robertson MN, Antonova-Koch Y, Avery V, Baell JB, Batchu H, Batra S, Burrows JN, Bhattacharyya S, Calderon F, Charman SA, Clark J, Crespo B, Dean M, Debbert SL, Delves M, Dennis AS, Deroose F, Duffy S, Fletcher S, Giaever G, Hallyburton I, Gamo FJ, Gebbia M, Guy RK, Hungerford Z, Kirk K, Lafuente-Monasterio MJ, Lee A, Meister S, Nislow C, Overington JP, Papadatos G, Patiny L, Pham J, Ralph SA, Ruecker A, Ryan E, Southan C, Srivastava K, Swain C, Tarnowski MJ, Thomson P, Turner P, Wallace IM, Wells TN, White K, White L, Willis P, Winzeler EA, Wittlin S, Todd MH. Williamson AE, et al. ACS Cent Sci. 2016 Oct 26;2(10):687-701. doi: 10.1021/acscentsci.6b00086. Epub 2016 Sep 14. ACS Cent Sci. 2016. PMID: 27800551 Free PMC article.
223 results