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Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids.
Nowrouzi A, Sertorio MG, Akbarpour M, Knoll M, Krunic D, Kuhar M, Schwager C, Brons S, Debus J, Wells SI, Wells JM, Abdollahi A. Nowrouzi A, et al. Among authors: wells si, wells jm. Cancers (Basel). 2020 Feb 18;12(2):469. doi: 10.3390/cancers12020469. Cancers (Basel). 2020. PMID: 32085439 Free PMC article.
The human DEK oncogene regulates DNA damage response signaling and repair.
Kavanaugh GM, Wise-Draper TM, Morreale RJ, Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF, Wells JM, Drissi R, Bissler JJ, Stambrook PJ, Andreassen PR, Wiesmüller L, Wells SI. Kavanaugh GM, et al. Among authors: wells si, wells jm. Nucleic Acids Res. 2011 Sep 1;39(17):7465-76. doi: 10.1093/nar/gkr454. Epub 2011 Jun 7. Nucleic Acids Res. 2011. PMID: 21653549 Free PMC article.
High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.
Chlon TM, Hoskins EE, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Chlon TM, et al. Among authors: wells si, wells jm. J Virol. 2014 Oct;88(19):11315-26. doi: 10.1128/JVI.01533-14. Epub 2014 Jul 16. J Virol. 2014. PMID: 25031356 Free PMC article.
Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage.
Chlon TM, Ruiz-Torres S, Maag L, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Chlon TM, et al. Among authors: wells si, wells jm. Stem Cell Reports. 2016 Jan 12;6(1):44-54. doi: 10.1016/j.stemcr.2015.12.001. Stem Cell Reports. 2016. PMID: 26771352 Free PMC article.
Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.
Serrano-Lopez J, Nattamai K, Pease NA, Shephard MS, Wellendorf AM, Sertorio M, Smith EA, Geiger H, Wells SI, Cancelas JA, Privette Vinnedge LM. Serrano-Lopez J, et al. Among authors: wells si. Exp Hematol. 2018 Mar;59:40-50.e3. doi: 10.1016/j.exphem.2017.12.009. Epub 2017 Dec 27. Exp Hematol. 2018. PMID: 29288703 Free PMC article.
Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification.
Trisno SL, Philo KED, McCracken KW, Catá EM, Ruiz-Torres S, Rankin SA, Han L, Nasr T, Chaturvedi P, Rothenberg ME, Mandegar MA, Wells SI, Zorn AM, Wells JM. Trisno SL, et al. Among authors: wells si, wells jm. Cell Stem Cell. 2018 Oct 4;23(4):501-515.e7. doi: 10.1016/j.stem.2018.08.008. Epub 2018 Sep 20. Cell Stem Cell. 2018. PMID: 30244869 Free PMC article.
Differential transcriptome response to proton versus X-ray radiation reveals novel candidate targets for combinatorial PT therapy in lymphoma.
Sertorio M, Nowrouzi A, Akbarpour M, Chetal K, Salomonis N, Brons S, Mascia A, Ionascu D, McCauley S, Kupneski T, Köthe A, Debus J, Perentesis JP, Abdollahi A, Zheng Y, Wells SI. Sertorio M, et al. Among authors: wells si. Radiother Oncol. 2021 Feb;155:293-303. doi: 10.1016/j.radonc.2020.10.024. Epub 2020 Oct 20. Radiother Oncol. 2021. PMID: 33096164 Free article.
Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin.
Ruiz-Torres S, Brusadelli MG, Witte DP, Wikenheiser-Brokamp KA, Sauter S, Nelson AS, Sertorio M, Chlon TM, Lane A, Mehta PA, Myers KC, Bedard MC, Pal B, Supp DM, Lambert PF, Komurov K, Kovacic MB, Davies SM, Wells SI. Ruiz-Torres S, et al. Among authors: wells si. Cell Stem Cell. 2021 Mar 4;28(3):424-435.e6. doi: 10.1016/j.stem.2020.10.012. Epub 2020 Nov 23. Cell Stem Cell. 2021. PMID: 33232662 Free PMC article.
81 results