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DEK proto-oncogene expression interferes with the normal epithelial differentiation program.
Wise-Draper TM, Morreale RJ, Morris TA, Mintz-Cole RA, Hoskins EE, Balsitis SJ, Husseinzadeh N, Witte DP, Wikenheiser-Brokamp KA, Lambert PF, Wells SI. Wise-Draper TM, et al. Among authors: wells si. Am J Pathol. 2009 Jan;174(1):71-81. doi: 10.2353/ajpath.2009.080330. Epub 2008 Nov 26. Am J Pathol. 2009. PMID: 19036808 Free PMC article.
The human DEK oncogene regulates DNA damage response signaling and repair.
Kavanaugh GM, Wise-Draper TM, Morreale RJ, Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF, Wells JM, Drissi R, Bissler JJ, Stambrook PJ, Andreassen PR, Wiesmüller L, Wells SI. Kavanaugh GM, et al. Among authors: wells si, wells jm. Nucleic Acids Res. 2011 Sep 1;39(17):7465-76. doi: 10.1093/nar/gkr454. Epub 2011 Jun 7. Nucleic Acids Res. 2011. PMID: 21653549 Free PMC article.
The fanconi anemia pathway limits human papillomavirus replication.
Hoskins EE, Morreale RJ, Werner SP, Higginbotham JM, Laimins LA, Lambert PF, Brown DR, Gillison ML, Nuovo GJ, Witte DP, Kim MO, Davies SM, Mehta PA, Butsch Kovacic M, Wikenheiser-Brokamp KA, Wells SI. Hoskins EE, et al. Among authors: wells si. J Virol. 2012 Aug;86(15):8131-8. doi: 10.1128/JVI.00408-12. Epub 2012 May 23. J Virol. 2012. PMID: 22623785 Free PMC article.
High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.
Chlon TM, Hoskins EE, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Chlon TM, et al. Among authors: wells si, wells jm. J Virol. 2014 Oct;88(19):11315-26. doi: 10.1128/JVI.01533-14. Epub 2014 Jul 16. J Virol. 2014. PMID: 25031356 Free PMC article.
81 results