Wells MC - Search Results

1

Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.

Copeland KW, Boezio AA, Cheung E, Lee J, Olivieri P, Schenkel LB, Wan Q, Wang W, Wells MC, Youngblood B, Gavva NR, Lehto SG, Geuns-Meyer S. Copeland KW, et al. Among authors: wells mc. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3464-8. doi: 10.1016/j.bmcl.2014.05.069. Epub 2014 Jun 6. Bioorg Med Chem Lett. 2014. PMID: 24953819

2

Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitors.

Schenkel LB, Huang X, Cheng A, Deak HL, Doherty E, Emkey R, Gu Y, Gunaydin H, Kim JL, Lee J, Loberg R, Olivieri P, Pistillo J, Tang J, Wan Q, Wang HL, Wang SW, Wells MC, Wu B, Yu V, Liu L, Geuns-Meyer S. Schenkel LB, et al. Among authors: wells mc. J Med Chem. 2011 Dec 22;54(24):8440-50. doi: 10.1021/jm200911r. Epub 2011 Nov 16. J Med Chem. 2011. PMID: 22087750

3

LC-MS/MS bioanalytical method development for AMG 900: resolution of an isobaric interference in rodent in vivo studies.

Be X, Moore ES, Zhao Z, Wells MC. Be X, et al. Among authors: wells mc. J Pharm Biomed Anal. 2013 Feb 23;74:171-7. doi: 10.1016/j.jpba.2012.10.026. Epub 2012 Nov 2. J Pharm Biomed Anal. 2013. PMID: 23245248

4

In vitro and in vivo pharmacokinetic characterizations of AMG 900, an orally bioavailable small molecule inhibitor of aurora kinases.

Huang L, Be X, Berry L, Moore E, Janosky B, Wells M, Pan WJ, Zhao Z, Lin MH. Huang L, et al. Xenobiotica. 2011 May;41(5):400-8. doi: 10.3109/00498254.2010.548534. Epub 2011 Feb 4. Xenobiotica. 2011. PMID: 21294625

5

Improved pharmacokinetics of AMG 517 through co-crystallization. Part 1: comparison of two acids with corresponding amide co-crystals.

Stanton MK, Kelly RC, Colletti A, Kiang YH, Langley M, Munson EJ, Peterson ML, Roberts J, Wells M. Stanton MK, et al. J Pharm Sci. 2010 Sep;99(9):3769-78. doi: 10.1002/jps.22181. J Pharm Sci. 2010. PMID: 20665842

6

Ratios of biliary glutathione disulfide (GSSG) to glutathione (GSH): a potential index to screen drug-induced hepatic oxidative stress in rats and mice.

Cao L, Waldon D, Teffera Y, Roberts J, Wells M, Langley M, Zhao Z. Cao L, et al. Anal Bioanal Chem. 2013 Mar;405(8):2635-42. doi: 10.1007/s00216-012-6661-8. Epub 2013 Feb 3. Anal Bioanal Chem. 2013. PMID: 23377112

7

Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioning.

Xu G, Chen JS, Phadnis R, Huang T, Uyeda C, Soto M, Stouch B, Wells MC, James CA, Carlson TJ. Xu G, et al. Among authors: wells mc. Bioanalysis. 2012 Aug;4(16):2037-47. doi: 10.4155/bio.12.167. Bioanalysis. 2012. PMID: 22946919

8

Improved pharmacokinetics of AMG 517 through co-crystallization part 2: analysis of 12 carboxylic acid co-crystals.

Stanton MK, Kelly RC, Colletti A, Langley M, Munson EJ, Peterson ML, Roberts J, Wells M. Stanton MK, et al. J Pharm Sci. 2011 Jul;100(7):2734-43. doi: 10.1002/jps.22502. Epub 2011 Feb 1. J Pharm Sci. 2011. PMID: 21287556

9

Medical Physics Leadership Academy Journal Club (Leadership Club) program: Two-year review in building a community of leaders.

Cetnar AJ, Hall K, Hirata EY, Wang D, Collins CE, Barreto IL, Edward SS, Kapadia A, Wells MC, Wilson JM, Xu Y, Johnson JL. Cetnar AJ, et al. Among authors: wells mc. J Appl Clin Med Phys. 2023 Nov;24(11):e14164. doi: 10.1002/acm2.14164. Epub 2023 Oct 3. J Appl Clin Med Phys. 2023. PMID: 37787494 Free PMC article.

10

Development and multi-institutional validation of a convolutional neural network to detect vertebral body mis-alignments in 2D x-ray setup images.

Petragallo R, Bertram P, Halvorsen P, Iftimia I, Low DA, Morin O, Narayanasamy G, Saenz DL, Sukumar KN, Valdes G, Weinstein L, Wells MC, Ziemer BP, Lamb JM. Petragallo R, et al. Among authors: wells mc. Med Phys. 2023 May;50(5):2662-2671. doi: 10.1002/mp.16359. Epub 2023 Mar 21. Med Phys. 2023. PMID: 36908243

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