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Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids.
Nowrouzi A, Sertorio MG, Akbarpour M, Knoll M, Krunic D, Kuhar M, Schwager C, Brons S, Debus J, Wells SI, Wells JM, Abdollahi A. Nowrouzi A, et al. Among authors: wells si, wells jm. Cancers (Basel). 2020 Feb 18;12(2):469. doi: 10.3390/cancers12020469. Cancers (Basel). 2020. PMID: 32085439 Free PMC article.
The human DEK oncogene regulates DNA damage response signaling and repair.
Kavanaugh GM, Wise-Draper TM, Morreale RJ, Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF, Wells JM, Drissi R, Bissler JJ, Stambrook PJ, Andreassen PR, Wiesmüller L, Wells SI. Kavanaugh GM, et al. Among authors: wells si, wells jm. Nucleic Acids Res. 2011 Sep 1;39(17):7465-76. doi: 10.1093/nar/gkr454. Epub 2011 Jun 7. Nucleic Acids Res. 2011. PMID: 21653549 Free PMC article.
High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.
Chlon TM, Hoskins EE, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Chlon TM, et al. Among authors: wells si, wells jm. J Virol. 2014 Oct;88(19):11315-26. doi: 10.1128/JVI.01533-14. Epub 2014 Jul 16. J Virol. 2014. PMID: 25031356 Free PMC article.
Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage.
Chlon TM, Ruiz-Torres S, Maag L, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Chlon TM, et al. Among authors: wells si, wells jm. Stem Cell Reports. 2016 Jan 12;6(1):44-54. doi: 10.1016/j.stemcr.2015.12.001. Stem Cell Reports. 2016. PMID: 26771352 Free PMC article.
Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification.
Trisno SL, Philo KED, McCracken KW, Catá EM, Ruiz-Torres S, Rankin SA, Han L, Nasr T, Chaturvedi P, Rothenberg ME, Mandegar MA, Wells SI, Zorn AM, Wells JM. Trisno SL, et al. Among authors: wells si, wells jm. Cell Stem Cell. 2018 Oct 4;23(4):501-515.e7. doi: 10.1016/j.stem.2018.08.008. Epub 2018 Sep 20. Cell Stem Cell. 2018. PMID: 30244869 Free PMC article.
Organoids by design.
Takebe T, Wells JM. Takebe T, et al. Among authors: wells jm. Science. 2019 Jun 7;364(6444):956-959. doi: 10.1126/science.aaw7567. Science. 2019. PMID: 31171692 Free PMC article.
Noncoding deletions reveal a gene that is critical for intestinal function.
Oz-Levi D, Olender T, Bar-Joseph I, Zhu Y, Marek-Yagel D, Barozzi I, Osterwalder M, Alkelai A, Ruzzo EK, Han Y, Vos ESM, Reznik-Wolf H, Hartman C, Shamir R, Weiss B, Shapiro R, Pode-Shakked B, Tatarskyy P, Milgrom R, Schvimer M, Barshack I, Imai DM, Coleman-Derr D, Dickel DE, Nord AS, Afzal V, van Bueren KL, Barnes RM, Black BL, Mayhew CN, Kuhar MF, Pitstick A, Tekman M, Stanescu HC, Wells JM, Kleta R, de Laat W, Goldstein DB, Pras E, Visel A, Lancet D, Anikster Y, Pennacchio LA. Oz-Levi D, et al. Among authors: wells jm. Nature. 2019 Jul;571(7763):107-111. doi: 10.1038/s41586-019-1312-2. Epub 2019 Jun 19. Nature. 2019. PMID: 31217582 Free PMC article.
Tissue Responses to Shiga Toxin in Human Intestinal Organoids.
Pradhan S, Karve SS, Weiss AA, Hawkins J, Poling HM, Helmrath MA, Wells JM, McCauley HA. Pradhan S, et al. Among authors: wells jm. Cell Mol Gastroenterol Hepatol. 2020;10(1):171-190. doi: 10.1016/j.jcmgh.2020.02.006. Epub 2020 Mar 5. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32145469 Free PMC article.
628 results