Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

515 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Discovery of VH domains that allosterically inhibit ENPP1.
Solomon PE, Bracken CJ, Carozza JA, Wang H, Young EP, Wellner A, Liu CC, Sweet-Cordero EA, Li L, Wells JA. Solomon PE, et al. Among authors: wells ja. Nat Chem Biol. 2024 Jan;20(1):30-41. doi: 10.1038/s41589-023-01368-5. Epub 2023 Jul 3. Nat Chem Biol. 2024. PMID: 37400538 Free PMC article.
Turning enzymes ON with small molecules.
Zorn JA, Wells JA. Zorn JA, et al. Among authors: wells ja. Nat Chem Biol. 2010 Mar;6(3):179-188. doi: 10.1038/nchembio.318. Nat Chem Biol. 2010. PMID: 20154666
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Lim SA, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Zhou XX, Hobman TC, Kortemme T, Wells JA. Glasgow A, et al. Among authors: wells ja. bioRxiv [Preprint]. 2020 Aug 4:2020.07.31.231746. doi: 10.1101/2020.07.31.231746. bioRxiv. 2020. PMID: 32766586 Free PMC article. Updated. Preprint.
Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike.
Bracken CJ, Lim SA, Solomon P, Rettko NJ, Nguyen DP, Zha BS, Schaefer K, Byrnes JR, Zhou J, Lui I, Liu J, Pance K; QCRG Structural Biology Consortium; Zhou XX, Leung KK, Wells JA. Bracken CJ, et al. Among authors: wells ja. bioRxiv [Preprint]. 2020 Aug 10:2020.08.08.242511. doi: 10.1101/2020.08.08.242511. bioRxiv. 2020. PMID: 32817948 Free PMC article. Updated. Preprint.
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
Bracken CJ, Lim SA, Solomon P, Rettko NJ, Nguyen DP, Zha BS, Schaefer K, Byrnes JR, Zhou J, Lui I, Liu J, Pance K; QCRG Structural Biology Consortium; Zhou XX, Leung KK, Wells JA. Bracken CJ, et al. Among authors: wells ja. Nat Chem Biol. 2021 Jan;17(1):113-121. doi: 10.1038/s41589-020-00679-1. Epub 2020 Oct 20. Nat Chem Biol. 2021. PMID: 33082574 Free PMC article.
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Lim SA, Zhou XX, Hobman TC, Kortemme T, Wells JA. Glasgow A, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28046-28055. doi: 10.1073/pnas.2016093117. Epub 2020 Oct 22. Proc Natl Acad Sci U S A. 2020. PMID: 33093202 Free PMC article.
515 results