Wells JA - Search Results

1

Theranostic Targeting of CUB Domain-Containing Protein 1 (CDCP1) in Multiple Subtypes of Bladder Cancer.

Chopra S, Trepka K, Sakhamuri S, Carretero-González A, Zhu J, Egusa E, Zhou J, Leung K, Zhao N, Hooshdaran N, Feng FY, Wells JA, Chou J, Evans MJ. Chopra S, et al. Among authors: wells ja. Clin Cancer Res. 2023 Apr 3;29(7):1232-1242. doi: 10.1158/1078-0432.CCR-22-1973. Clin Cancer Res. 2023. PMID: 36648492 Free PMC article.

2

Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins.

Martinko AJ, Truillet C, Julien O, Diaz JE, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans MJ, Wells JA. Martinko AJ, et al. Among authors: wells ja. Elife. 2018 Jan 23;7:e31098. doi: 10.7554/eLife.31098. Elife. 2018. PMID: 29359686 Free PMC article.

3

Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif.

Mou Y, Zhou XX, Leung K, Martinko AJ, Yu JY, Chen W, Wells JA. Mou Y, et al. Among authors: wells ja. J Am Chem Soc. 2018 Dec 5;140(48):16615-16624. doi: 10.1021/jacs.8b08402. Epub 2018 Nov 19. J Am Chem Soc. 2018. PMID: 30398859

4

Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.

Leung KK, Nguyen A, Shi T, Tang L, Ni X, Escoubet L, MacBeth KJ, DiMartino J, Wells JA. Leung KK, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):695-700. doi: 10.1073/pnas.1813666116. Epub 2018 Dec 24. Proc Natl Acad Sci U S A. 2019. PMID: 30584089 Free PMC article.

5

Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling.

Wei J, Leung K, Truillet C, Ruggero D, Wells JA, Evans MJ. Wei J, et al. Among authors: wells ja. Mol Cell Proteomics. 2020 Feb;19(2):294-307. doi: 10.1074/mcp.RA119.001785. Epub 2019 Dec 2. Mol Cell Proteomics. 2020. PMID: 31792071 Free PMC article.

6

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.

Leung KK, Wilson GM, Kirkemo LL, Riley NM, Coon JJ, Wells JA. Leung KK, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7764-7775. doi: 10.1073/pnas.1917947117. Epub 2020 Mar 23. Proc Natl Acad Sci U S A. 2020. PMID: 32205440 Free PMC article.

7

Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer.

Moroz A, Wang YH, Sharib JM, Wei J, Zhao N, Huang Y, Chen Z, Martinko AJ, Zhuo J, Lim SA, Zhang LH, Seo Y, Carlin S, Leung KK, Collisson EA, Kirkwood KS, Wells JA, Evans MJ. Moroz A, et al. Among authors: wells ja. Clin Cancer Res. 2020 Jul 15;26(14):3608-3615. doi: 10.1158/1078-0432.CCR-20-0268. Epub 2020 Apr 27. Clin Cancer Res. 2020. PMID: 32341034 Free PMC article.

8

Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike.

Bracken CJ, Lim SA, Solomon P, Rettko NJ, Nguyen DP, Zha BS, Schaefer K, Byrnes JR, Zhou J, Lui I, Liu J, Pance K; QCRG Structural Biology Consortium; Zhou XX, Leung KK, Wells JA. Bracken CJ, et al. Among authors: wells ja. bioRxiv [Preprint]. 2020 Aug 10:2020.08.08.242511. doi: 10.1101/2020.08.08.242511. bioRxiv. 2020. PMID: 32817948 Free PMC article. Updated. Preprint.

9

Targeting Phosphotyrosine in Native Proteins with Conditional, Bispecific Antibody Traps.

Zhou XX, Bracken CJ, Zhang K, Zhou J, Mou Y, Wang L, Cheng Y, Leung KK, Wells JA. Zhou XX, et al. Among authors: wells ja. J Am Chem Soc. 2020 Oct 14;142(41):17703-17713. doi: 10.1021/jacs.0c08458. Epub 2020 Sep 29. J Am Chem Soc. 2020. PMID: 32924468 Free PMC article.

10

Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding.

Byrnes JR, Zhou XX, Lui I, Elledge SK, Glasgow JE, Lim SA, Loudermilk RP, Chiu CY, Wang TT, Wilson MR, Leung KK, Wells JA. Byrnes JR, et al. Among authors: wells ja. mSphere. 2020 Sep 16;5(5):e00802-20. doi: 10.1128/mSphere.00802-20. mSphere. 2020. PMID: 32938700 Free PMC article.

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