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How Social Considerations Improve the Equity and Effectiveness of Ecosystem Restoration.
Löfqvist S, Kleinschroth F, Bey A, de Bremond A, DeFries R, Dong J, Fleischman F, Lele S, Martin DA, Messerli P, Meyfroidt P, Pfeifer M, Rakotonarivo SO, Ramankutty N, Ramprasad V, Rana P, Rhemtulla JM, Ryan CM, Vieira ICG, Wells GJ, Garrett RD. Löfqvist S, et al. Among authors: wells gj. Bioscience. 2022 Dec 14;73(2):134-148. doi: 10.1093/biosci/biac099. eCollection 2023 Feb. Bioscience. 2022. PMID: 36896142 Free PMC article.
Nature's contribution to poverty alleviation, human wellbeing and the SDGs.
Poudyal M, Kraft F, Wells G, Das A, Attiwilli S, Schreckenberg K, Lele S, Daw T, Torres-Vitolas C, Setty S, Adams H, Ahmad S, Ryan C, Fisher J, Robinson B, Jones JPG, Homewood K, Bluwstein J, Keane A, Macamo C, Mugi LM. Poudyal M, et al. Sci Data. 2024 Feb 22;11(1):229. doi: 10.1038/s41597-024-02967-0. Sci Data. 2024. PMID: 38388572 Free PMC article.
Strategies to mitigate the bioactivation of 2-anilino-7-aryl-pyrrolo[2,1-f][1,2,4]triazines: identification of orally bioavailable, efficacious ALK inhibitors.
Mesaros EF, Thieu TV, Wells GJ, Zificsak CA, Wagner JC, Breslin HJ, Tripathy R, Diebold JL, McHugh RJ, Wohler AT, Quail MR, Wan W, Lu L, Huang Z, Albom MS, Angeles TS, Wells-Knecht KJ, Aimone LD, Cheng M, Ator MA, Ott GR, Dorsey BD. Mesaros EF, et al. Among authors: wells gj. J Med Chem. 2012 Jan 12;55(1):115-25. doi: 10.1021/jm2010767. Epub 2011 Dec 29. J Med Chem. 2012. PMID: 22141319
2,7-Pyrrolo[2,1-f][1,2,4]triazines as JAK2 inhibitors: modification of target structure to minimize reactive metabolite formation.
Weinberg LR, Albom MS, Angeles TS, Breslin HJ, Gingrich DE, Huang Z, Lisko JG, Mason JL, Milkiewicz KL, Thieu TV, Underiner TL, Wells GJ, Wells-Knecht KJ, Dorsey BD. Weinberg LR, et al. Among authors: wells gj. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7325-30. doi: 10.1016/j.bmcl.2011.10.032. Epub 2011 Oct 14. Bioorg Med Chem Lett. 2011. PMID: 22041060
2,7-disubstituted-pyrrolo[2,1-f][1,2,4]triazines: new variant of an old template and application to the discovery of anaplastic lymphoma kinase (ALK) inhibitors with in vivo antitumor activity.
Ott GR, Wells GJ, Thieu TV, Quail MR, Lisko JG, Mesaros EF, Gingrich DE, Ghose AK, Wan W, Lu L, Cheng M, Albom MS, Angeles TS, Huang Z, Aimone LD, Ator MA, Ruggeri BA, Dorsey BD. Ott GR, et al. Among authors: wells gj. J Med Chem. 2011 Sep 22;54(18):6328-41. doi: 10.1021/jm200758k. Epub 2011 Aug 22. J Med Chem. 2011. PMID: 21859094
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