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Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Carrer A, Trefely S, Zhao S, Campbell SL, Norgard RJ, Schultz KC, Sidoli S, Parris JLD, Affronti HC, Sivanand S, Egolf S, Sela Y, Trizzino M, Gardini A, Garcia BA, Snyder NW, Stanger BZ, Wellen KE. Carrer A, et al. Among authors: wellen ke. Cancer Discov. 2019 Mar;9(3):416-435. doi: 10.1158/2159-8290.CD-18-0567. Epub 2019 Jan 9. Cancer Discov. 2019. PMID: 30626590 Free PMC article.
Obesity, cancer, and acetyl-CoA metabolism.
Lee JV, Shah SA, Wellen KE. Lee JV, et al. Among authors: wellen ke. Drug Discov Today Dis Mech. 2013 Jun;10(1-2):e55-e61. doi: 10.1016/j.ddmec.2013.03.005. Drug Discov Today Dis Mech. 2013. PMID: 23878588 Free PMC article.
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation.
Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, Won KJ, Chodosh LA, Garcia BA, Stanger BZ, Feldman MD, Blair IA, Wellen KE. Lee JV, et al. Among authors: wellen ke. Cell Metab. 2014 Aug 5;20(2):306-319. doi: 10.1016/j.cmet.2014.06.004. Epub 2014 Jul 3. Cell Metab. 2014. PMID: 24998913 Free PMC article.
Metabolism and epigenetics: a link cancer cells exploit.
Carrer A, Wellen KE. Carrer A, et al. Among authors: wellen ke. Curr Opin Biotechnol. 2015 Aug;34:23-9. doi: 10.1016/j.copbio.2014.11.012. Epub 2014 Nov 29. Curr Opin Biotechnol. 2015. PMID: 25461508 Free PMC article. Review.
Molecular biology: Salvaging the genome.
Sivanand S, Wellen KE. Sivanand S, et al. Among authors: wellen ke. Nature. 2015 Aug 6;524(7563):40-1. doi: 10.1038/nature14638. Epub 2015 Jul 22. Nature. 2015. PMID: 26200344 No abstract available.
Dysregulated metabolism contributes to oncogenesis.
Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team. Hirschey MD, et al. Among authors: wellen ke. Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Semin Cancer Biol. 2015. PMID: 26454069 Free PMC article. Review.
A cancerous web: signaling, metabolism, and the epigenome.
Lee JV, Shah S, Carrer A, Wellen KE. Lee JV, et al. Among authors: wellen ke. Mol Cell Oncol. 2014 Oct 30;2(2):e965620. doi: 10.4161/23723548.2014.965620. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2014. PMID: 27308412 Free PMC article.
83 results