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TIGIT blockade repolarizes AML-associated TIGIT+ M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck F, Fischer B, Witt M, Muschhammer J, Oelrich J, da Costa Avelar PH, Tsoka S, Bullinger L, Seubert E, Smit DJ, Bokemeyer C, Ackermann C, Wellbrock J, Haag F, Fiedler W. Brauneck F, et al. Among authors: wellbrock j. J Immunother Cancer. 2022 Dec;10(12):e004794. doi: 10.1136/jitc-2022-004794. J Immunother Cancer. 2022. PMID: 36549780 Free PMC article.
CD146: a new partner for VEGFR2.
Wellbrock J, Fiedler W. Wellbrock J, et al. Blood. 2012 Sep 13;120(11):2164-5. doi: 10.1182/blood-2012-07-439646. Blood. 2012. PMID: 22977083 Free article. No abstract available.
Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma.
Ben-Batalla I, Schultze A, Wroblewski M, Erdmann R, Heuser M, Waizenegger JS, Riecken K, Binder M, Schewe D, Sawall S, Witzke V, Cubas-Cordova M, Janning M, Wellbrock J, Fehse B, Hagel C, Krauter J, Ganser A, Lorens JB, Fiedler W, Carmeliet P, Pantel K, Bokemeyer C, Loges S. Ben-Batalla I, et al. Among authors: wellbrock j. Blood. 2013 Oct 3;122(14):2443-52. doi: 10.1182/blood-2013-03-491431. Epub 2013 Aug 27. Blood. 2013. PMID: 23982172 Free article.
Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prolactin pathway.
Oliveira-Ferrer L, Wellbrock J, Bartsch U, Penas EM, Hauschild J, Klokow M, Bokemeyer C, Fiedler W, Schuch G. Oliveira-Ferrer L, et al. Among authors: wellbrock j. Mol Cancer. 2013 Nov 20;12(1):144. doi: 10.1186/1476-4598-12-144. Mol Cancer. 2013. PMID: 24257371 Free PMC article.
Overexpression of Gremlin-1 in patients with Loeys-Dietz syndrome: implications on pathophysiology and early disease detection.
Wellbrock J, Sheikhzadeh S, Oliveira-Ferrer L, Stamm H, Hillebrand M, Keyser B, Klokow M, Vohwinkel G, Bonk V, Otto B, Streichert T, Balabanov S, Hagel C, Rybczynski M, Bentzien F, Bokemeyer C, von Kodolitsch Y, Fiedler W. Wellbrock J, et al. PLoS One. 2014 Aug 12;9(8):e104742. doi: 10.1371/journal.pone.0104742. eCollection 2014. PLoS One. 2014. PMID: 25116393 Free PMC article.
ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.
Kebenko M, Drenckhan A, Gros SJ, Jücker M, Grabinski N, Ewald F, Grottke A, Schultze A, Izbicki JR, Bokemeyer C, Wellbrock J, Fiedler W. Kebenko M, et al. Among authors: wellbrock j. Cell Signal. 2015 Feb;27(2):373-81. doi: 10.1016/j.cellsig.2014.11.022. Epub 2014 Nov 27. Cell Signal. 2015. PMID: 25435423
Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
Wellbrock J, Latuske E, Köhler J, Wagner K, Stamm H, Vettorazzi E, Vohwinkel G, Klokow M, Uibeleisen R, Ehm P, Riecken K, Loges S, Thol F, Schubert C, Amling M, Jücker M, Bokemeyer C, Heuser M, Krauter J, Fiedler W. Wellbrock J, et al. Clin Cancer Res. 2015 May 15;21(10):2388-98. doi: 10.1158/1078-0432.CCR-14-1059. Epub 2015 Mar 5. Clin Cancer Res. 2015. PMID: 25745035
46 results