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Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy.
Redondo-Muñoz M, Rodriguez-Baena FJ, Aldaz P, Caballé-Mestres A, Moncho-Amor V, Otaegi-Ugartemendia M, Carrasco-Garcia E, Olias-Arjona A, Lasheras-Otero I, Santamaria E, Bocanegra A, Chocarro L, Grier A, Dzieciatkowska M M, Bigas C, Martin J, Urdiroz-Urricelqui U, Marzo F, Santamaria E, Kochan G, Escors D, Larrayoz IM, Heyn H, D'Alessandro A, Attolini CS, Matheu A, Wellbrock C, Benitah SA, Sanchez-Laorden B, Arozarena I. Redondo-Muñoz M, et al. Among authors: wellbrock c. Nat Metab. 2023 Sep;5(9):1544-1562. doi: 10.1038/s42255-023-00861-4. Epub 2023 Aug 10. Nat Metab. 2023. PMID: 37563469 Free PMC article.
Targeting invasive properties of melanoma cells.
Arozarena I, Wellbrock C. Arozarena I, et al. Among authors: wellbrock c. FEBS J. 2017 Jul;284(14):2148-2162. doi: 10.1111/febs.14040. Epub 2017 Mar 1. FEBS J. 2017. PMID: 28196297 Free article. Review.
The Regulators of Peroxisomal Acyl-Carnitine Shuttle CROT and CRAT Promote Metastasis in Melanoma.
Lasheras-Otero I, Feliu I, Maillo A, Moreno H, Redondo-Muñoz M, Aldaz P, Bocanegra A, Olias-Arjona A, Lecanda F, Fernandez-Irigoyen J, Santamaria E, Larrayoz IM, Gomez-Cabrero D, Wellbrock C, Vicent S, Arozarena I. Lasheras-Otero I, et al. Among authors: wellbrock c. J Invest Dermatol. 2023 Feb;143(2):305-316.e5. doi: 10.1016/j.jid.2022.08.038. Epub 2022 Sep 1. J Invest Dermatol. 2023. PMID: 36058299 Free article.
Overcoming resistance to BRAF inhibitors.
Arozarena I, Wellbrock C. Arozarena I, et al. Among authors: wellbrock c. Ann Transl Med. 2017 Oct;5(19):387. doi: 10.21037/atm.2017.06.09. Ann Transl Med. 2017. PMID: 29114545 Free PMC article. Review.
Identification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma.
Aldaz P, Auzmendi-Iriarte J, Durántez M, Lasheras-Otero I, Carrasco-Garcia E, Zelaya MV, Bragado L, Olías-Arjona A, Egaña L, Samprón N, Morilla I, Redondo-Muñoz M, Rico M, Squatrito M, Maria-Alonso M, Fernández-Irigoyen J, Santamaria E, Larráyoz IM, Wellbrock C, Matheu A, Arozarena I. Aldaz P, et al. Among authors: wellbrock c. Cancers (Basel). 2021 Jan 19;13(2):361. doi: 10.3390/cancers13020361. Cancers (Basel). 2021. PMID: 33478100 Free PMC article.
Cooperative behaviour and phenotype plasticity evolve during melanoma progression.
Rowling EJ, Miskolczi Z, Nagaraju R, Wilcock DJ, Wang P, Telfer B, Li Y, Lasheras-Otero I, Redondo-Muñoz M, Sharrocks AD, Arozarena I, Wellbrock C. Rowling EJ, et al. Among authors: wellbrock c. Pigment Cell Melanoma Res. 2020 Sep;33(5):695-708. doi: 10.1111/pcmr.12873. Epub 2020 Mar 20. Pigment Cell Melanoma Res. 2020. PMID: 32145051 Free PMC article.
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