Weitzman MD - Search Results

1

Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction.

Singh N, Lee YG, Shestova O, Ravikumar P, Hayer KE, Hong SJ, Lu XM, Pajarillo R, Agarwal S, Kuramitsu S, Orlando EJ, Mueller KT, Good CR, Berger SL, Shalem O, Weitzman MD, Frey NV, Maude SL, Grupp SA, June CH, Gill S, Ruella M. Singh N, et al. Among authors: weitzman md. Cancer Discov. 2020 Apr;10(4):552-567. doi: 10.1158/2159-8290.CD-19-0813. Epub 2020 Jan 30. Cancer Discov. 2020. PMID: 32001516 Free PMC article.

2

Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.

Green AM, Budagyan K, Hayer KE, Reed MA, Savani MR, Wertheim GB, Weitzman MD. Green AM, et al. Among authors: weitzman md. Cancer Res. 2017 Sep 1;77(17):4579-4588. doi: 10.1158/0008-5472.CAN-16-3394. Epub 2017 Jun 27. Cancer Res. 2017. PMID: 28655787 Free PMC article.

3

Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing.

Herrmann C, Dybas JM, Liddle JC, Price AM, Hayer KE, Lauman R, Purman CE, Charman M, Kim ET, Garcia BA, Weitzman MD. Herrmann C, et al. Among authors: weitzman md. Nat Microbiol. 2020 Oct;5(10):1217-1231. doi: 10.1038/s41564-020-0750-9. Epub 2020 Jul 13. Nat Microbiol. 2020. PMID: 32661314 Free PMC article.

4

STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury.

Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E 3rd, Beers MF, Weitzman MD, Morrisey EE, Worthen GS. Paris AJ, et al. Among authors: weitzman md. Nat Cell Biol. 2020 Oct;22(10):1197-1210. doi: 10.1038/s41556-020-0569-x. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989251 Free PMC article.

5

Direct RNA sequencing reveals m⁶A modifications on adenovirus RNA are necessary for efficient splicing.

Price AM, Hayer KE, McIntyre ABR, Gokhale NS, Abebe JS, Della Fera AN, Mason CE, Horner SM, Wilson AC, Depledge DP, Weitzman MD. Price AM, et al. Among authors: weitzman md. Nat Commun. 2020 Nov 26;11(1):6016. doi: 10.1038/s41467-020-19787-6. Nat Commun. 2020. PMID: 33243990 Free PMC article.

6

Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity.

Green AM, DeWeerd RA, O'Leary DR, Hansen AR, Hayer KE, Kulej K, Dineen AS, Szeto JH, Garcia BA, Weitzman MD. Green AM, et al. Among authors: weitzman md. EMBO Rep. 2021 Sep 6;22(9):e52145. doi: 10.15252/embr.202052145. Epub 2021 Aug 4. EMBO Rep. 2021. PMID: 34347354 Free PMC article.

7

Adenovirus prevents dsRNA formation by promoting efficient splicing of viral RNA.

Price AM, Steinbock RT, Di C, Hayer KE, Li Y, Herrmann C, Parenti NA, Whelan JN, Weiss SR, Weitzman MD. Price AM, et al. Among authors: weitzman md. Nucleic Acids Res. 2022 Feb 22;50(3):1201-1220. doi: 10.1093/nar/gkab896. Nucleic Acids Res. 2022. PMID: 34671803 Free PMC article.

8

DRUMMER-rapid detection of RNA modifications through comparative nanopore sequencing.

Abebe JS, Price AM, Hayer KE, Mohr I, Weitzman MD, Wilson AC, Depledge DP. Abebe JS, et al. Among authors: weitzman md. Bioinformatics. 2022 May 26;38(11):3113-3115. doi: 10.1093/bioinformatics/btac274. Bioinformatics. 2022. PMID: 35426900 Free PMC article.

9

Antigen glycosylation regulates efficacy of CAR T cells targeting CD19.

Heard A, Landmann JH, Hansen AR, Papadopolou A, Hsu YS, Selli ME, Warrington JM, Lattin J, Chang J, Ha H, Haug-Kroeper M, Doray B, Gill S, Ruella M, Hayer KE, Weitzman MD, Green AM, Fluhrer R, Singh N. Heard A, et al. Among authors: weitzman md. Nat Commun. 2022 Jun 11;13(1):3367. doi: 10.1038/s41467-022-31035-7. Nat Commun. 2022. PMID: 35690611 Free PMC article.

10

Novel viral splicing events and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts.

Price AM, Steinbock RT, Lauman R, Charman M, Hayer KE, Kumar N, Halko E, Lum KK, Wei M, Wilson AC, Garcia BA, Depledge DP, Weitzman MD. Price AM, et al. Among authors: weitzman md. PLoS Pathog. 2022 Sep 12;18(9):e1010797. doi: 10.1371/journal.ppat.1010797. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36095031 Free PMC article.

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